Zebrafish in toxicology and environmental health

K Bambino, J Chu - Current topics in developmental biology, 2017 - Elsevier
As manufacturing processes and development of new synthetic compounds increase to
keep pace with the expanding global demand, environmental health, and the effects of …

Zebrafish as a model system to study toxicology

YJ Dai, YF Jia, N Chen, WP Bian, QK Li… - Environmental …, 2014 - Wiley Online Library
Monitoring and assessing the effects of contaminants in the aquatic eco‐environment is
critical in protecting human health and the environment. The zebrafish has been widely used …

The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing

S Scholz, S Fischer, U Gündel, E Küster… - … science and pollution …, 2008 - Springer
Background, aim, and scope The use of fish embryos is not regulated by current legislations
on animal welfare and is therefore considered as a refinement, if not replacement of animal …

[图书][B] The toxicology of fishes

RT Di Giulio, DE Hinton - 2008 - taylorfrancis.com
When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

Zebrafish—As an integrative model for twenty‐first century toxicity testing

NS Sipes, S Padilla, TB Knudsen - Birth Defects Research Part …, 2011 - Wiley Online Library
The zebrafish embryo is a useful small model for investigating vertebrate development
because of its transparency, low cost, transgenic and morpholino capabilities, conservation …

Molecular mechanisms of crude oil developmental toxicity in fish

JP Incardona - Archives of Environmental Contamination and …, 2017 - Springer
With major oil spills in Korea, the United States, and China in the past decade, there has
been a dramatic increase in the number of studies characterizing the developmental toxicity …

Cardiotoxicity of uremic toxins: a driver of cardiorenal syndrome

S Lekawanvijit - Toxins, 2018 - mdpi.com
Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …

Zebrafish as a mainstream model for in vivo systems pharmacology and toxicology

CA MacRae, RT Peterson - Annual Review of Pharmacology …, 2023 - annualreviews.org
Pharmacology and toxicology are part of a much broader effort to understand the
relationship between chemistry and biology. While biomedicine has necessarily focused on …

cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling

MD Houslay, GS Baillie, DH Maurice - Circulation research, 2007 - Am Heart Assoc
Cyclic AMP regulates a vast number of distinct events in all cells. Early studies established
that its hydrolysis by cyclic nucleotide phosphodiesterases (PDEs) controlled both the …

Cardiorenal syndrome: the emerging role of protein-bound uremic toxins

S Lekawanvijit, AR Kompa, BH Wang, DJ Kelly… - Circulation …, 2012 - Am Heart Assoc
Cardiorenal syndrome is a condition in which a complex interrelationship between cardiac
dysfunction and renal dysfunction exists. Despite advances in treatment of both …