A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading
Deformational loading represents a primary component of the chondrocyte physical
environment in vivo. This review summarizes our experience with physiologic deformational …
environment in vivo. This review summarizes our experience with physiologic deformational …
Frontiers in Tissue Engineering: In Vitro Modulation of Chondrogenesis.
LE Freed, I Martin… - Clinical Orthopaedics and …, 1999 - journals.lww.com
Cartilage tissue engineering can provide functional cartilaginous constructs that can be
used for controlled in vitro studies of chondrogenesis and potentially for in vivo articular …
used for controlled in vitro studies of chondrogenesis and potentially for in vivo articular …
An additive manufacturing‐based PCL–alginate–chondrocyte bioprinted scaffold for cartilage tissue engineering
Regenerative medicine is targeted to improve, restore or replace damaged tissues or organs
using a combination of cells, materials and growth factors. Both tissue engineering and …
using a combination of cells, materials and growth factors. Both tissue engineering and …
The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering
In the literature there are conflicting reports on the optimal scaffold mean pore size required
for successful bone tissue engineering. This study set out to investigate the effect of mean …
for successful bone tissue engineering. This study set out to investigate the effect of mean …
Hyaluronic acid‐based bioink composition enabling 3D bioprinting and improving quality of deposited cartilaginous extracellular matrix
J Hauptstein, T Böck, M Bartolf‐Kopp… - Advanced …, 2020 - Wiley Online Library
In 3D bioprinting, bioinks with high concentrations of polymeric materials are frequently used
to enable fabrication of 3D cell‐hydrogel constructs with sufficient stability. However, this is …
to enable fabrication of 3D cell‐hydrogel constructs with sufficient stability. However, this is …
Functional arteries grown in vitro
LE Niklason, J Gao, WM Abbott, KK Hirschi, S Houser… - Science, 1999 - science.org
A tissue engineering approach was developed to produce arbitrary lengths of vascular graft
material from smooth muscle and endothelial cells that were derived from a biopsy of …
material from smooth muscle and endothelial cells that were derived from a biopsy of …
Biodegradable polymer scaffolds for tissue engineering
LE Freed, G Vunjak-Novakovic, RJ Biron, DB Eagles… - Bio/technology, 1994 - nature.com
Synthetic polymer scaffolds designed for cell transplantation were reproducibly made on a
large scale and studied with respect to biocompatibility, structure and biodegradation rate …
large scale and studied with respect to biocompatibility, structure and biodegradation rate …
Effect of collagen turnover on the accumulation of advanced glycation end products
N Verzijl, J DeGroot, SR Thorpe, RA Bank… - Journal of Biological …, 2000 - ASBMB
Collagen molecules in articular cartilage have an exceptionally long lifetime, which makes
them susceptible to the accumulation of advanced glycation end products (AGEs). In fact, in …
them susceptible to the accumulation of advanced glycation end products (AGEs). In fact, in …
Water-based polyurethane 3D printed scaffolds with controlled release function for customized cartilage tissue engineering
KC Hung, CS Tseng, LG Dai, S Hsu - Biomaterials, 2016 - Elsevier
Conventional 3D printing may not readily incorporate bioactive ingredients for controlled
release because the process often involves the use of heat, organic solvent, or crosslinkers …
release because the process often involves the use of heat, organic solvent, or crosslinkers …
Effect of pore size on ECM secretion and cell growth in gelatin scaffold for articular cartilage tissue engineering
SM Lien, LY Ko, TJ Huang - Acta biomaterialia, 2009 - Elsevier
A novel method for the preparation of gelatin scaffolds was designed by varying the
crosslinking temperature. Four pore size ranges of genipin-crosslinked gelatin scaffolds …
crosslinking temperature. Four pore size ranges of genipin-crosslinked gelatin scaffolds …