Leishmaniasis (visceral and cutaneous), Chagas disease and human African
trypanosomiasis cause substantial death and morbidity, particularly in low-and middle …

Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects millions of
people in the Americas and across the world, leading to considerable morbidity and …

Trypanosoma cruzi (T. cruzi) is the etiological agent of Chagas cardiomyopathy. In the
present study, we investigated the role of extracellular vesicles (Ev) in shaping the …

Chagas disease is the most important protozoan infection in the Americas, and constitutes a
significant public health concern throughout the world. Development of new medications …

Introduction Chagas cardiomyopathy, a disease caused by Trypanosoma cruzi (T. cruzi)
infection, is a major contributor to heart failure in Latin America. There are significant gaps in …

Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in
the chronic phase requires positive results from two different IgG serological tests. Three …

Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Introduction: As benznidazole is the first-line treatment for patients with Chagas disease,
rational chemotherapy strategies are required based on the critical analysis of the evidence …

Aberrant adenosine diphosphate-ribose (ADP)-ribosylation of proteins and nucleic acids is
associated with multiple disease processes such as infections and chronic inflammatory …