Diagnosis and epidemiology of leptospirosis

M Picardeau - Médecine et maladies infectieuses, 2013 - Elsevier
Leptospirosis is a zoonosis found worldwide, the main reservoir of which is the rat. Human
infection generally results from exposure to contaminated river or lake water or animals …

Leptospirosis: aspects of innate immunity, immunopathogenesis and immune evasion from the complement system

TR Fraga, AS Barbosa, L Isaac - Scandinavian journal of …, 2011 - Wiley Online Library
Leptospirosis is a neglected infectious disease caused by spirochetes from the genus
Leptospira. It constitutes a major public health problem in developing countries, with …

Actionable diagnosis of neuroleptospirosis by next-generation sequencing

MR Wilson, SN Naccache, E Samayoa… - … England Journal of …, 2014 - Mass Medical Soc
A 14-year-old boy with severe combined immunodeficiency presented three times to a
medical facility over a period of 4 months with fever and headache that progressed to …

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance

J Guglielmini, P Bourhy, O Schiettekatte… - PLoS neglected …, 2019 - journals.plos.org
Leptospira is a highly heterogeneous bacterial genus that can be divided into three
evolutionary lineages and> 300 serovars. The causative agents of leptospirosis are …

Epidemiology of Leptospira Transmitted by Rodents in Southeast Asia

JF Cosson, M Picardeau, M Mielcarek… - PLoS Neglected …, 2014 - journals.plos.org
Background Leptospirosis is the most common bacterial zoonoses and has been identified
as an important emerging global public health problem in Southeast Asia. Rodents are …

A Single Multilocus Sequence Typing (MLST) Scheme for Seven Pathogenic Leptospira Species

S Boonsilp, J Thaipadungpanit… - PLoS neglected …, 2013 - journals.plos.org
Background The available Leptospira multilocus sequence typing (MLST) scheme
supported by a MLST website is limited to L. interrogans and L. kirschneri. Our aim was to …

Leptospira spp., a genus in the stage of diversity and genomic data expansion

K Caimi, P Ruybal - Infection, Genetics and Evolution, 2020 - Elsevier
Leptospirosis is a widespread global zoonotic bacterial disease with a noteworthy human-
animal-ecosystem interface. The disease presents different clinical manifestations and a …

Prospective evaluation of three rapid diagnostic tests for diagnosis of human leptospirosis

MGA Goris, MMG Leeflang, M Loden… - PLoS neglected …, 2013 - journals.plos.org
Background Diagnosis of leptospirosis by the microscopic agglutination test (MAT) or by
culture is confined to specialized laboratories. Although ELISA techniques are more …

Human leptospirosis on Reunion Island, Indian Ocean: are rodents the (only) ones to blame?

V Guernier, E Lagadec, C Cordonin… - PLoS neglected …, 2016 - journals.plos.org
Background Although leptospirosis is a zoonosis of major concern on tropical islands, the
molecular epidemiology of the disease aiming at linking human cases to specific animal …