MicroRNAs (miRNAs) are endogenous, non‐coding RNAs, which have evoked a great deal
of interest due to their importance in many aspects of homeostasis and diseases …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

Cardiovascular diseases (CVDs) have become a serious threat to human life and health.
Though many drugs acting via different mechanism of action are available in the market as …

The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Background Micro RNA s (mi RNA s) play a key role in the development of heart failure, and
recent studies have shown that the muscle‐specific miR‐1 is a key regulator of cardiac …

Background: Fibrosis is a hallmark of many myocardial pathologies and contributes to
distorted organ architecture and function. Recent studies have identified premature …

Cardiomyocyte function depends on coordinated movements of calcium into and out of the
cell and the proper delivery of ATP to energy-utilizing enzymes. Defects in calcium-handling …

Background—Several microRNAs (miRs) have been shown to regulate gene expression in
the heart, and dysregulation of their expression has been linked to cardiac disease. miR-378 …

Adeno-associated virus serotype 9 (AAV9) has enhanced capsid-associated tropism for
cardiac muscle and the ability to cross the blood-brain barrier compared to other AAV …

Myocardial infarction (MI) is defined as cardiomyocyte death in a clinical context consistent
with ischemic insult. MI remains one of the leading causes of morbidity and mortality …