How far are we from reliable metabolomics-based biomarkers? The often-overlooked importance of addressing inter-individual variability factors
Á González-Domínguez… - Biochimica et Biophysica …, 2023 - Elsevier
Metabolomics has proven great potential to unravel the molecular basis of diseases.
However, most attempts aimed at identifying reliable metabolomics-based biomarkers for …
However, most attempts aimed at identifying reliable metabolomics-based biomarkers for …
[HTML][HTML] Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage
Á González-Domínguez, T Belmonte… - Reviews in Endocrine …, 2023 - Springer
The incidence of childhood obesity and metabolic syndrome has grown notably in the last
years, becoming major public health burdens in developed countries. Nowadays, oxidative …
years, becoming major public health burdens in developed countries. Nowadays, oxidative …
[HTML][HTML] Parental obesity predisposes to exacerbated metabolic and inflammatory disturbances in childhood obesity within the framework of an altered profile of trace …
Á González-Domínguez, L Jurado-Sumariva… - Nutrition & …, 2024 - nature.com
Background Family history of obesity is known to increase the odds of developing childhood
obesity in the offspring, but its influence in underlying molecular complications remains …
obesity in the offspring, but its influence in underlying molecular complications remains …
QComics: Recommendations and Guidelines for Robust, Easily Implementable and Reportable Quality Control of Metabolomics Data
Á González-Domínguez, N Estanyol-Torres… - Analytical …, 2024 - ACS Publications
The implementation of quality control strategies is crucial to ensure the reproducibility,
accuracy, and meaningfulness of metabolomics data. However, this pivotal step is often …
accuracy, and meaningfulness of metabolomics data. However, this pivotal step is often …
Association between childhood obesity, trace elements, and heavy metals: Recent discoveries and future perspectives
Á González‐Domínguez, L Jurado‐Sumariva… - Obesity …, 2024 - Wiley Online Library
Trace elements and heavy metals play pivotal roles in health status by regulating a myriad of
vital biological functions. Abnormal metal homeostasis has been linked to a constellation of …
vital biological functions. Abnormal metal homeostasis has been linked to a constellation of …
[HTML][HTML] Metal homeostasis and exposure in distinct phenotypic subtypes of insulin resistance among children with obesity
Á González-Domínguez, M Millán-Martínez… - Nutrients, 2023 - mdpi.com
Background: Trace elements and heavy metals have proven pivotal roles in childhood
obesity and insulin resistance. However, growing evidence suggests that insulin resistance …
obesity and insulin resistance. However, growing evidence suggests that insulin resistance …