Dopamine: functions, signaling, and association with neurological diseases
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
The origin of NMDA receptor hypofunction in schizophrenia
K Nakazawa, K Sapkota - Pharmacology & therapeutics, 2020 - Elsevier
Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …
[图书][B] Consciousness and the brain: Deciphering how the brain codes our thoughts
S Dehaene - 2014 - books.google.com
WINNER OF THE 2014 BRAIN PRIZE From the acclaimed author of Reading in the Brain
and How We Learn, a breathtaking look at the new science that can track consciousness …
and How We Learn, a breathtaking look at the new science that can track consciousness …
The physiology, signaling, and pharmacology of dopamine receptors
JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …
[HTML][HTML] Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses
AFT Arnsten, MJ Wang, CD Paspalas - Neuron, 2012 - cell.com
This review describes unique neuromodulatory influences on working memory prefrontal
cortical (PFC) circuits that coordinate cognitive strength with arousal state. Working memory …
cortical (PFC) circuits that coordinate cognitive strength with arousal state. Working memory …
[HTML][HTML] NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex
Neurons in the primate dorsolateral prefrontal cortex (dlPFC) generate persistent firing in the
absence of sensory stimulation, the foundation of mental representation. Persistent firing …
absence of sensory stimulation, the foundation of mental representation. Persistent firing …
The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia
KS Na, HY Jung, YK Kim - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Schizophrenia is a serious mental illness with chronic symptoms and significant impairment
in psychosocial functioning. Although novel antipsychotics have been developed, the …
in psychosocial functioning. Although novel antipsychotics have been developed, the …
Caffeine and adenosine
JA Ribeiro, AM Sebastiao - Journal of Alzheimer's disease, 2010 - content.iospress.com
Caffeine causes most of its biological effects via antagonizing all types of adenosine
receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons …
receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons …
Identification of loci associated with schizophrenia by genome-wide association and follow-up
We carried out a genome-wide association study of schizophrenia (479 cases, 2,937
controls) and tested loci with P< 10− 5 in up to 16,726 additional subjects. Of 12 loci …
controls) and tested loci with P< 10− 5 in up to 16,726 additional subjects. Of 12 loci …
Calcium signalling remodelling and disease
MJ Berridge - Biochemical Society Transactions, 2012 - portlandpress.com
A wide range of Ca2+ signalling systems deliver the spatial and temporal Ca2+ signals
necessary to control the specific functions of different cell types. Release of Ca2+ by Ins P 3 …
necessary to control the specific functions of different cell types. Release of Ca2+ by Ins P 3 …