Pathogenesis of Concanavalin A induced autoimmune hepatitis in mice

J Hao, W Sun, H Xu - International Immunopharmacology, 2022 - Elsevier
Autoimmune hepatitis (AIH) is an autoimmune disease characterized by liver parenchymal
destruction and chronic fibrosis. Its exact etiology and pathogenesis are not yet fully …

[HTML][HTML] New insights into iNKT cells and their roles in liver diseases

X Gu, Q Chu, X Ma, J Wang, C Chen, J Guan… - Frontiers in …, 2022 - frontiersin.org
Natural killer T cells (NKTs) are an important part of the immune system. Since their
discovery in the 1990s, researchers have gained deeper insights into the physiology and …

[HTML][HTML] Corilagin ameliorates con A-induced hepatic injury by restricting M1 macrophage polarization

F Yan, D Cheng, H Wang, M Gao, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of
diverse liver diseases. However, treatment choice for immune-mediated hepatic injury …

Prenyllongnols A–D, New Prenylated Acylphloroglucinols that Fight Concanavalin A-Induced Autoimmune Hepatitis

Z Shi, X Zhao, F Song, Z Hou, X Hao… - Journal of Agricultural …, 2023 - ACS Publications
Autoimmune hepatitis is a serious hepatic disorder with unknown nosogenesis, and natural
products have been deemed to be one of the most significant sources of new drugs against …

The gut microbiome and autoimmune hepatitis: implications for early diagnostic biomarkers and novel therapies

L Li, Y Kang - Molecular Nutrition & Food Research, 2023 - Wiley Online Library
Autoimmune hepatitis (AIH) is a serious chronic liver disease that may last for decades and
eventually develop into cirrhosis and liver failure. In recent years, people have paid more …

[HTML][HTML] Daidzein ameliorated concanavalin A-induced liver injury through the Akt/GSK-3β/Nrf2 pathway in mice

SL Li, R Cao, XF Hu, P Xiong, GY Zhao… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Daidzein is a soybean isoflavone that has been shown in previous studies to
have anti-inflammatory and antioxidant effects. However, it remains unknown whether …

[HTML][HTML] Summary of natural products ameliorate concanavalin a-induced liver injury: structures, sources, pharmacological effects, and mechanisms of action

SRM Ibrahim, A Sirwi, BG Eid, SGA Mohamed… - Plants, 2021 - mdpi.com
Liver diseases represent a threat to human health and are a significant cause of mortality
and morbidity worldwide. Autoimmune hepatitis (AIH) is a progressive and chronic hepatic …

[HTML][HTML] Comprehensive immune cell analysis of human menstrual-blood-derived stem cells therapy to concanavalin A hepatitis

F Zhang, L Fan, Q Liu, S Tang, S Zhang, L Xiao… - Frontiers in …, 2022 - frontiersin.org
Autoimmune hepatitis is an autoimmune disease with increasing occurrence worldwide. The
most common and convenient mouse model is the concanavalin A (ConA) mouse model …

[HTML][HTML] Inhibitory Effects of Epipolythiodioxopiperazine Fungal Metabolites on Isocitrate Lyase in the Glyoxylate Cycle of Candida albicans

JY Hwang, B Chung, OS Kwon, SC Park, E Cho… - Marine Drugs, 2021 - mdpi.com
Four epipolythiodioxopiperazine fungal metabolites (1–4) isolated from the sponge-derived
Aspergillus quadrilineatus FJJ093 were evaluated for their capacity to inhibit isocitrate lyase …

Asperemestrins A–D, Emestrin Hybrid Polymers with Bridged Skeletons from the Endophytic Fungus Aspergillus nidulans

Q Li, A Fu, M Wei, Y Xiao, J Yin, J Huang, XN Li… - Organic …, 2022 - ACS Publications
Four emestrin hybrid polymers, asperemestrins A–D (1–4, respectively), were isolated from
the fungus Aspergillus nidulans. Asperemestrins A–C are the first examples of emestrin …