[PDF][PDF] Hope on the horizon: novel fungal treatments in development

AM Rauseo, A Coler-Reilly, L Larson… - Open Forum Infectious …, 2020 - academic.oup.com
The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …

Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections

S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …

[HTML][HTML] Dermatophyte resistance to antifungal drugs: mechanisms and prospectus

NM Martinez-Rossi, TA Bitencourt, NTA Peres… - Frontiers in …, 2018 - frontiersin.org
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …

[HTML][HTML] Development and research progress of anti-drug resistant fungal drugs

X Cui, L Wang, Y Lue, C Yue - Journal of Infection and Public Health, 2022 - Elsevier
With the widespread use of immunosuppressive agents and the increase in patients with
severe infections, the incidence of fungal infections worldwide has increased year by year …

[HTML][HTML] Contemporary techniques and potential transungual drug delivery nanosystems for the treatment of onychomycosis

WH Abd-Elsalam, SM Abouelatta - AAPS PharmSciTech, 2023 - Springer
The humanoid nail is considered an exceptional protective barrier that is formed mainly from
keratin. Onychomycosis is the cause of 50% of nail infections that is generally caused by …

[HTML][HTML] Newer topical treatments in skin and nail dermatophyte infections

K Sahni, S Singh, S Dogra - Indian dermatology online journal, 2018 - journals.lww.com
Dermatophytes are amongst the most common causative agents of fungal infections
worldwide and widespread in the developing countries. Various studies have found the …

[PDF][PDF] Anti-diabetic activity of lycopene niosomes: Experimental observation

PK Sharma, P Saxena, A Jaswanth… - J. Pharm. Drug …, 2017 - researchgate.net
Liposomes are associated with problems related to stability such as aggregation, fusion,
leakage, and sedimentation on storage [9]. Niosomes are non-ionic surfactant based …

A novel apremilast nail lacquer formulation for the treatment of nail psoriasis

AS Kushwaha, MA Repka, S Narasimha Murthy - AAPS PharmSciTech, 2017 - Springer
The objective was to prepare a novel nail lacquer formulation to improve the ungual and
trans-ungual delivery of apremilast for the potential treatment of nail psoriasis. Nail lacquer …

New and promising chemotherapeutics for emerging infections involving drug-resistant non-albicans Candida species

LN Silva, TP de Mello… - Current Topics in …, 2019 - ingentaconnect.com
Fungal infections are a veritable public health problem worldwide. The increasing number of
patient populations at risk (eg transplanted individuals, cancer patients, and HIV-infected …

AR-12 Exhibits Direct and Host-Targeted Antibacterial Activity toward Mycobacterium abscessus

S Zhang, Y Zou, Q Guo, J Chen, L Xu… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Therapeutic options for Mycobacterium abscessus infections are extremely limited. New or
repurposed drugs are needed. The anti-M. abscessus activity of AR-12 (OSU-03012) …