Gram-negative bacteria are intrinsically resistant to many antibiotics, due in large part to the
permeability barrier formed by their cell envelope. The complex and synergistic interplay of …

The sophisticated envelope of Gram-negative bacteria modulates the uptake of small
molecules in a side-chain-sensitive manner. Despite intensive theoretical and experimental …

Antibiotic resistance of Gram-negative bacteria is largely attributed to the low permeability of
their outer membrane (OM). Recently, we disclosed the eNTRy rules, a key lesson of which …

Transmembrane β-barrel proteins are key systems for transport phenomena in biology.
Based on their broad substrate specificity, they represent good candidates for present and …

The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the
steadily emerging antibiotic resistance, novel tools are needed for early and easy …

Antibiotic resistance, particularly among Gram-negative bacteria, poses a significant
healthcare challenge due to their ability to evade antibiotic action through various …

Background: Plants, including invasive ones, can play a significant role in the fight against
antibiotic resistance and the search for new antimicrobials. Aims: The present study aimed at …

Passive transport of molecules through nanopores is characterized by the interaction of
molecules with pore internal walls and by a general crowding effect due to the constricted …

Modern medicine relies upon antibiotics, but we have arrived to the point where our inability
to come up with new effective molecules against resistant pathogens, together with the …

Antibiotic resistance has been a growing public health crisis since the 1980s. Therefore, it is
essential not only to continue to develop novel antibiotics but also to develop new methods …