The RNA polymerase II carboxy-terminal domain (CTD) code

D Eick, M Geyer - Chemical reviews, 2013 - ACS Publications
The smallest viable unit of life is the cell. From bacteria to mammals, all cells use the same
nucleic acid-based universal code for the maintenance and inheritance of genetic …

The general transcription factors of RNA polymerase II.

G Orphanides, T Lagrange… - Genes & …, 1996 - genesdev.cshlp.org
The general transcription factors of RNA polymerase II. Publisher Logo Genes &
Development Skip to main page content HOME ABOUT SUBMIT SUBSCRIBE ADVERTISE …

Elongation by RNA polymerase II: the short and long of it

RJ Sims, R Belotserkovskaya… - Genes & …, 2004 - genesdev.cshlp.org
Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP
II) have identified this stage as a dynamic and highly regulated step of the transcription …

DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

AR Lehmann - Biochimie, 2003 - Elsevier
Xeroderma pigmentosum (XP), Cockayne syndrome (CS) and trichothiodystrophy (TTD) are
genetic disorders with very different clinical features, but all associated with defects in …

Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins

GW Hart - Annual review of biochemistry, 1997 - annualreviews.org
Modification of Ser and Thr residues by attachment of O-linked N-acetylglucosamine [Ser
(Thr)-O-GlcNAcylation] to eukaryotic nuclear and cytosolic proteins is as dynamic and …

Identification of multiple cyclin subunits of human P-TEFb

J Peng, Y Zhu, JT Milton, DH Price - Genes & development, 1998 - genesdev.cshlp.org
The transition from abortive into productive elongation is proposed to be controlled by a
positive transcription elongation factor b (P-TEFb) through phosphorylation of the carboxy …

RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc

WG Kelly, ME Dahmus, GW Hart - Journal of Biological Chemistry, 1993 - Elsevier
The largest subunit of mammalian RNA polymerase II (RNAP II) contains at its carboxyl
terminus an unusual domain consisting of 52 tandem repeats of the consensus sequence …

A structural perspective of CTD function

A Meinhart, T Kamenski, S Hoeppner… - Genes & …, 2005 - genesdev.cshlp.org
The C-terminal domain (CTD) of RNA polymerase II (Pol II) integrates nuclear events by
binding proteins involved in mRNA biogenesis. CTD-binding proteins recognize a specific …

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II.

A DvIR, SR Peterson, MW Knuth… - Proceedings of the …, 1992 - National Acad Sciences
The carboxyl-terminal domain of RNA polymerase II contains a tandemly repeated
heptapeptide sequence. Previous work has shown that this sequence is phosphorylated at …

Tails of RNA polymerase II

JL Corden - Trends in biochemical sciences, 1990 - cell.com
In addition to the [3'homology regions, the largest subunit of RNA polymerase II, from a
variety of species, contains an unusual repetitive domain that is not found in the homologous …