Abstract Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness
such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei …

Abstract Currently, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2,
formerly known as 2019-nCoV, the causative pathogen of Coronavirus Disease 2019 …

Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in
December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The …

COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread across the globe, posing an enormous threat to public health and safety …

We prepared the three-dimensional model of the SARS-CoV-2 (aka 2019-nCoV) 3C-like
protease (3CL pro) using the crystal structure of the highly similar (96% identity) ortholog …

Despite intense research there is currently no effective vaccine available against the new
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 …

Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open …

COVID-19 has become a global pandemic and there is an urgent call for developing drugs
against the virus (SARS-CoV-2). The 3C-like protease (3CLpro) of SARS-CoV-2 is a …

The COVID‐19 pandemic caused by SARS‐CoV‐2 infection is spreading at an alarming
rate and has created an unprecedented health emergency around the globe. There is no …