Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Iodine is a micronutrient needed for the production of thyroid hormones, which regulate
metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid …

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Prompt diagnosis
by newborn screening (NBS) leading to early and adequate treatment results in grossly …

Thyroid hormone has important effects on almost every organ system and plays a crucial
role in normal growth and neurologic development. Congenital hypothyroidism affects …

Congenital hypothyroidism occurs in approximately 1 in 2000 newborns and can have
devastating neurodevelopmental consequences if not detected and treated promptly. While …

Thyroid hormone has important physiologic functions in nearly every organ system. The
critical role of thyroid hormone in growth and in physical and neurologic development lends …

When newborn screening (NBS) for congenital hypothyroidism (CH) using thyroid-
stimulating hormone (TSH) as a primary screening test was introduced, typical TSH …

The evaluation and management of hypothyroidism in children are similar to adults, but
there are important differences based on the dependence on normal thyroid function for …

Objective To determine if newborn screening (NBS) programs for congenital hypothyroidism
in the US use thyroid-stimulating hormone (TSH) cutoffs that are age adjusted to account for …

Laboratory medicine approaches the evaluation of thyroid function mostly through the single
determination of the blood level of thyroid stimulating hormone (TSH). Some authors have …