Degradable and recyclable polymers by reversible deactivation radical polymerization

MR Martinez, K Matyjaszewski - CCS Chemistry, 2022 - chinesechemsoc.org
Reversible deactivation radical polymerization (RDRP) provides unprecedented control over
polymer composition, size, functionality, and topology. Various materials, such as linear …

Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance

Z Ge, S Liu - Chemical Society Reviews, 2013 - pubs.rsc.org
Self-assembled nanostructures of amphiphilic and double hydrophilic block copolymers
have been increasingly utilized as potent polymeric nanocarriers of therapeutic drugs …

ATRP in the design of functional materials for biomedical applications

DJ Siegwart, JK Oh, K Matyjaszewski - Progress in polymer science, 2012 - Elsevier
Atom Transfer Radical Polymerization (ATRP) is an effective technique for the design and
preparation of multifunctional, nanostructured materials for a variety of applications in …

Engineering nanoparticles for targeted delivery of nucleic acid therapeutics in tumor

Y Xiao, K Shi, Y Qu, B Chu, Z Qian - Molecular Therapy Methods & Clinical …, 2019 - cell.com
In the past 10 years, with the increase of investment in clinical nano-gene therapy, there are
many trials that have been discontinued due to poor efficacy and serious side effects …

[HTML][HTML] Main-chain water-soluble polyphosphoesters: Multi-functional polymers as degradable PEG-alternatives for biomedical applications

C Pelosi, MR Tinè, FR Wurm - European polymer journal, 2020 - Elsevier
Polyphosphoesters (PPEs) are a class of (bio) degradable polymers with high chemical
versatility and functionality. In particular, water-soluble PPEs with the phosphoester group in …

Stimuli-responsive tertiary amine methacrylate-based block copolymers: Synthesis, supramolecular self-assembly and functional applications

J Hu, G Zhang, Z Ge, S Liu - Progress in Polymer Science, 2014 - Elsevier
In the past decade, responsive polymers exhibiting reversible or irreversible changes in
physical properties and/or chemical structures in response to external stimuli have been …

Double hydrophilic copolymers–synthetic approaches, architectural variety, and current application fields

A Nabiyan, JB Max, FH Schacher - Chemical Society Reviews, 2022 - pubs.rsc.org
Solubility and functionality of polymeric materials are essential properties determining their
role in any application. In that regard, double hydrophilic copolymers (DHC) are typically …

Polymer vectors via controlled/living radical polymerization for gene delivery

FJ Xu, WT Yang - Progress in Polymer Science, 2011 - Elsevier
The design of efficient gene delivery vectors is a challenging task in gene therapy. Recent
progress in living/controlled radical polymerizations (LRPs), in particular atom transfer …

A photo, temperature, and pH responsive spiropyran-functionalized polymer: Synthesis, self-assembly and controlled release

F Jiang, S Chen, Z Cao, G Wang - Polymer, 2016 - Elsevier
Here we report a photo, temperature and pH responsive copolymer which was conveniently
synthesized by quaternization between the spiropyran derivative (SPN–Cl) and …

Bioresponsive matrices in drug delivery

JO You, D Almeda, GJC Ye, DT Auguste - Journal of biological …, 2010 - Springer
For years, the field of drug delivery has focused on (1) controlling the release of a
therapeutic and (2) targeting the therapeutic to a specific cell type. These research …