The advantages and limitations of trait analysis with GWAS: a review
Over the last 10 years, high-density SNP arrays and DNA re-sequencing have illuminated
the majority of the genotypic space for a number of organisms, including humans, maize …
the majority of the genotypic space for a number of organisms, including humans, maize …
Meta-analysis methods for genome-wide association studies and beyond
E Evangelou, JPA Ioannidis - Nature Reviews Genetics, 2013 - nature.com
Meta-analysis of genome-wide association studies (GWASs) has become a popular method
for discovering genetic risk variants. Here, we overview both widely applied and newer …
for discovering genetic risk variants. Here, we overview both widely applied and newer …
[图书][B] Nutrition in the Prevention and Treatment of Disease
CJ Boushey, AM Coulston, CL Rock, E Monsen - 2001 - books.google.com
As we enter the 21st century, a new era of nutrition in the prevention and treatment of
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …
Statistical analysis strategies for association studies involving rare variants
V Bansal, O Libiger, A Torkamani… - Nature Reviews Genetics, 2010 - nature.com
The limitations of genome-wide association (GWA) studies that focus on the phenotypic
influence of common genetic variants have motivated human geneticists to consider the …
influence of common genetic variants have motivated human geneticists to consider the …
Review of current methods, applications, and data management for the bioinformatics analysis of whole exome sequencing
The advent of next-generation sequencing technologies has greatly promoted advances in
the study of human diseases at the genomic, transcriptomic, and epigenetic levels. Exome …
the study of human diseases at the genomic, transcriptomic, and epigenetic levels. Exome …
Comparison of statistical tests for disease association with rare variants
In anticipation of the availability of next‐generation sequencing data, there is increasing
interest in investigating association between complex traits and rare variants (RVs). In …
interest in investigating association between complex traits and rare variants (RVs). In …
APOE* E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease
Alzheimer's disease (AD) age of onset (ADAOO) varies greatly between individuals, with
unique causal mutations suggesting the role of modifying genetic and environmental …
unique causal mutations suggesting the role of modifying genetic and environmental …
Computational and statistical approaches to analyzing variants identified by exome sequencing
Computational and statistical approaches to analyzing variants identified by exome sequencing
| Genome Biology Skip to main content SpringerLink Account Menu Find a journal Publish with …
| Genome Biology Skip to main content SpringerLink Account Menu Find a journal Publish with …
A comparison between genotyping-by-sequencing and array-based scoring of SNPs for genomic prediction accuracy in winter wheat
The utilization of DNA molecular markers in plant breeding to maximize selection response
via marker-assisted selection (MAS) and genomic selection (GS) has revolutionized plant …
via marker-assisted selection (MAS) and genomic selection (GS) has revolutionized plant …
The PHF21B gene is associated with major depression and modulates the stress response
Major depressive disorder (MDD) affects around 350 million people worldwide; however, the
underlying genetic basis remains largely unknown. In this study, we took into account that …
underlying genetic basis remains largely unknown. In this study, we took into account that …