Population genomics of bacterial host adaptation
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …
Indeed, an estimated 60% of all human pathogens have originated from other animal …
[HTML][HTML] One chromosome, one contig: complete microbial genomes from long-read sequencing and assembly
S Koren, AM Phillippy - Current opinion in microbiology, 2015 - Elsevier
Highlights•We describe three long-read sequencing technologies and their
characteristics.•We describe available algorithms for long-read assembly and their …
characteristics.•We describe available algorithms for long-read assembly and their …
Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary
Genome-wide association studies (GWAS) have become indispensable in human medicine
and genomics, but very few have been carried out on bacteria. Here we introduce Scoary …
and genomics, but very few have been carried out on bacteria. Here we introduce Scoary …
Reactive oxygen species are regulated by immune deficiency and Toll pathways in determining the host specificity of honeybee gut bacteria
Host specificity is observed in gut symbionts of diverse animal lineages. But how hosts
maintain symbionts while rejecting their close relatives remains elusive. We use eusocial …
maintain symbionts while rejecting their close relatives remains elusive. We use eusocial …
[HTML][HTML] Host genetic regulation of human gut microbial structural variation
Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
Twenty years of bacterial genome sequencing
Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus
influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades …
influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades …
Microbial genome-wide association studies: lessons from human GWAS
The reduced costs of sequencing have led to whole-genome sequences for a large number
of microorganisms, enabling the application of microbial genome-wide association studies …
of microorganisms, enabling the application of microbial genome-wide association studies …
Pathogenomics of Emerging Campylobacter Species
Campylobacter is among the four main causes of gastroenteritis worldwide and has
increased in both developed and developing countries over the last 10 years. The vast …
increased in both developed and developing countries over the last 10 years. The vast …
Genome evolution and the emergence of pathogenicity in avian Escherichia coli
Chickens are the most common birds on Earth and colibacillosis is among the most common
diseases affecting them. This major threat to animal welfare and safe sustainable food …
diseases affecting them. This major threat to animal welfare and safe sustainable food …
Identifying lineage effects when controlling for population structure improves power in bacterial association studies
SG Earle, CH Wu, J Charlesworth, N Stoesser… - Nature …, 2016 - nature.com
Bacteria pose unique challenges for genome-wide association studies because of strong
structuring into distinct strains and substantial linkage disequilibrium across the genome 1 …
structuring into distinct strains and substantial linkage disequilibrium across the genome 1 …