[HTML][HTML] Sulodexide in the treatment of patients with early stages of COVID-19: a randomized controlled trial

AJ Gonzalez-Ochoa, JD Raffetto… - Thrombosis and …, 2021 - thieme-connect.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce several
vascular endothelial-dependent systemic complications, and sulodexide has pleiotropic …

[HTML][HTML] Mechanisms of lower extremity vein dysfunction in chronic venous disease and implications in management of varicose veins

JD Raffetto, RA Khalil - Vessel plus, 2021 - ncbi.nlm.nih.gov
Chronic venous disease (CVD) is a common venous disorder of the lower extremities. CVD
can be manifested as varicose veins (VVs), with dilated and tortuous veins, dysfunctional …

The blood pressure lowering potential of sulodexide–a systematic review and meta‐analysis

RHG Olde Engberink, NMG Rorije… - British journal of …, 2015 - Wiley Online Library
Aims Sulodexide is a highly purified mixture of glycosaminoglycans that has been studied
for its anti‐albuminuric potential. Considering the effects of glycosaminoglycans on …

Sulodexide promotes arterial relaxation via endothelium-dependent nitric oxide-mediated pathway

JD Raffetto, F Calanni, P Mattana, RA Khalil - Biochemical pharmacology, 2019 - Elsevier
Sulodexide (SDX) is a highly purified glycosaminoglycan with antithrombotic and
profibrinolytic properties and reported benefits in thrombotic and atherosclerotic vascular …

Soluble syndecan-1 and glycosaminoglycans in preeclamptic and normotensive pregnancies

H Hassani Lahsinoui, F Amraoui, LJA Spijkers… - Scientific reports, 2021 - nature.com
Preeclampsia, an important cause of maternal and fetal morbidity and mortality, is
associated with increased sFLT1 levels and with structural and functional damage to the …

Localized scleroderma (morphea). Diagnostic and therapeutic recommendations of the Polish Dermatological Society

D Krasowska, L Rudnicka… - Dermatology Review …, 2019 - termedia.pl
Localized scleroderma (morphea) is a chronic autoimmune disease of the connective tissue.
Its etiopathogenesis is unknown. Most often the disease affects the skin, but may also …

Sulodexide Increases Glutathione Synthesis and Causes Pro-Reducing Shift in Glutathione-Redox State in HUVECs Exposed to Oxygen–Glucose Deprivation …

K Bontor, B Gabryel - Molecules, 2022 - mdpi.com
Sulodexide (SDX), a purified glycosaminoglycan mixture used to treat vascular diseases,
has been reported to exert endothelial protective effects against ischemic injury. However …

Comparative anticoagulant and thrombin generation inhibitory profile of heparin, sulodexide and its components

F Siddiqui, D Hoppensteadt… - Clinical and Applied …, 2020 - journals.sagepub.com
Introduction: Sulodexide represents a mixture of fast-moving heparin (FMH) and dermatan
sulfate (DS) and has been used for the management of venous diseases such as DVT and …

Sulodexide Inhibits Arterial Contraction via the Endothelium-Dependent Nitric Oxide Pathway

N Ors Yildirim, AK Yildirim, M Demeli Ertus… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Sulodexide (SDX) is a drug known for restoring the glycocalyx,
thereby offering endothelial protection and regulating permeability. Additionally, it has …

Guidelines on the prevention and treatment of venous thromboembolism in cancer patients treated surgically, including patients under 18 years of age

Z Krasiński, T Urbanek, A Undas… - Acta …, 2021 - journals.viamedica.pl
Venous thromboembolism (VTE) is one of the most dangerous complications of cancer.
Oncological treatment, surgeries and advanced-stage cancer are only some of the risk …