Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Fibrosis is a chronic and progressive disorder characterized by excessive deposition of
extracellular matrix, which leads to scarring and loss of function of the affected organ or …

Methods This was a retrospective, observational study conducted in a 35-bed ICU at Wuhan
Jinyintan Hospital. The institutional ethics review board approved this study (KY-2020 …

Background Whether respiratory physiology of COVID-19-induced respiratory failure is
different from acute respiratory distress syndrome (ARDS) of other etiologies is unclear. We …

Rationale: Response to positive end-expiratory pressure (PEEP) in acute respiratory
distress syndrome depends on recruitability. We propose a bedside approach to estimate …

Acute respiratory distress syndrome (ARDS) is a clinical entity that acutely affects the lung
parenchyma, and is characterized by diffuse alveolar damage and increased pulmonary …

Rationale: Defining lung recruitability is needed for safe positive end-expiratory pressure
(PEEP) selection in mechanically ventilated patients. However, there is no simple bedside …

Background A large proportion of patients with a SARS-Cov-2-associated respiratory failure
develop an acute respiratory distress syndrome (ARDS). It has been recently suggested that …

Background Respiratory mechanics is a key element to monitor mechanically ventilated
patients and guide ventilator settings. Besides the usual basic assessments, some more …

Background In acute respiratory distress syndrome (ARDS), non-ventilated perfused regions
coexist with non-perfused ventilated regions within lungs. The number of unmatched regions …