Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production
In order to decrease carbon emissions and negative environmental impacts of various
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …
Sustainable production of natural phenolics for functional food applications
R Mark, X Lyu, JJL Lee, R Parra-Saldívar… - Journal of Functional …, 2019 - Elsevier
Phenolics are a class of plant-derived natural secondary metabolites with good anticancer,
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …
Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli
SH Yoon, SH Lee, A Das, HK Ryu, HJ Jang… - Journal of …, 2009 - Elsevier
The increased synthesis of building blocks of IPP (isopentenyl diphosphate) and DMAPP
(dimethylallyl diphosphate) through metabolic engineering is a way to enhance the …
(dimethylallyl diphosphate) through metabolic engineering is a way to enhance the …
Biosynthesis of coenzyme Q in eukaryotes
M Kawamukai - Bioscience, biotechnology, and biochemistry, 2016 - academic.oup.com
Coenzyme Q (CoQ) is a component of the electron transport chain that participates in
aerobic cellular respiration to produce ATP. In addition, CoQ acts as an electron acceptor in …
aerobic cellular respiration to produce ATP. In addition, CoQ acts as an electron acceptor in …
Metabolic engineering and synthetic biology approaches driving isoprenoid production in Escherichia coli
Isoprenoids comprise the largest family of natural organic compounds with many useful
applications in the pharmaceutical, nutraceutical, and industrial fields. Rapid developments …
applications in the pharmaceutical, nutraceutical, and industrial fields. Rapid developments …
Cellular factories for coenzyme Q10 production
SQE Lee, TS Tan, M Kawamukai, ES Chen - Microbial cell factories, 2017 - Springer
Abstract Coenzyme Q 10 (CoQ 10), a benzoquinone present in most organisms, plays an
important role in the electron-transport chain, and its deficiency is associated with various …
important role in the electron-transport chain, and its deficiency is associated with various …
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway
C Wang, SH Yoon, AA Shah, YR Chung… - Biotechnology and …, 2010 - Wiley Online Library
Farnesol (FOH) production has been carried out in metabolically engineered Escherichia
coli. FOH is formed through the depyrophosphorylation of farnesyl pyrophosphate (FPP) …
coli. FOH is formed through the depyrophosphorylation of farnesyl pyrophosphate (FPP) …
4-Hydroxybenzoic acid—a versatile platform intermediate for value-added compounds
Hydroxybenzoic acid (4-HBA) has recently emerged as a promising intermediate for several
value-added bioproducts with potential biotechnological applications in food, cosmetics …
value-added bioproducts with potential biotechnological applications in food, cosmetics …
De novo production of the monoterpenoid geranic acid by metabolically engineered Pseudomonas putida
J Mi, D Becher, P Lubuta, S Dany, K Tusch… - Microbial cell …, 2014 - Springer
Background Production of monoterpenoids as valuable chemicals using recombinant
microbes is a growing field of interest. Unfortunately, antimicrobial activity of most …
microbes is a growing field of interest. Unfortunately, antimicrobial activity of most …
Alternative metabolic pathways and strategies to high-titre terpenoid production in Escherichia coli
MA Rinaldi, CA Ferraz, NS Scrutton - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2021 Terpenoids are a diverse group of chemicals used in a wide range of
industries. Microbial terpenoid production has the potential to displace traditional …
industries. Microbial terpenoid production has the potential to displace traditional …