Solid tumors are active tissues containing hypoxic regions and producing metabolic acids.
By decreasing pH, cancer cells create a hostile environment for surrounding host cells and …

Potential metal chelators containing one or several acyltetronic acid moieties were prepared
from cyclic or acyclic amines and polyamines, and from bis (phenols) by reaction with 1–4 …

Coumarins, quinolinones, tetramic and tetronic acid analogues, play an integral role in
biological systems and forms a variety of complexes with environmentally active metals. A …

The analysis of labile ions that easily decompose at various stages of the analytical process
is a significant challenge for any analytical method. In this thesis, a new analytical approach …

This document is a presentation and discussion on three projects in three parts. Part One is
a detailed summary of organic chemistry efforts in the synthesis of a model of the natural …