Malignant pleural effusions (MPE) are a common pathology, treated by respiratory
physicians and thoracic surgeons alike. In recent years, several well-designed randomized …

Background The use of antithrombotic agents, including anticoagulants, antiplatelet agents,
and thrombolytics has increased over the last decade and is expected to continue to rise …

Pleural Disease This review discusses the substantial advances that have been made in our
understanding of pleural biology and related pathophysiology, as well as in the …

The American Association for Thoracic Surgery consensus guidelines for the management of
empyema - The Journal of Thoracic and Cardiovascular Surgery Skip to Main Content …

Thoracic ultrasound is increasingly considered to be an essential tool for the pulmonologist.
It is used in diverse clinical scenarios, including as an adjunct to clinical decision making for …

Background Adjustment for prognostic covariates can lead to increased power in the
analysis of randomized trials. However, adjusted analyses are not often performed in …

Artificial intelligence (AI) is transforming healthcare delivery. The digital revolution in
medicine and healthcare information is prompting a staggering growth of data intertwined …

Objectives To assess how often stratified randomisation is used, whether analysis adjusted
for all balancing variables, and whether the method of randomisation was adequately …

Many clinical trials restrict randomisation using stratified blocks or minimisation to balance
prognostic factors across treatment groups. It is widely acknowledged in the statistical …

Background Empyema refers to pus in the pleural space, commonly due to adjacent
pneumonia, chest wall injury, or a complication of thoracic surgery. A range of therapeutic …