Pulmonary delivery of lipid-based nanotherapeutics by inhalation presents an
advantageous alternative to oral and intravenous routes of administration that avoids …

CHAIR: Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA TASK FORCE 1:
Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland …

Abstract Tacrolimus (FK-506) is an immunosuppressant agent that acts by a variety of
different mechanisms which include inhibition of calcineurin. It is used as a therapeutic …

Success in cardiac transplantation has been achieved by the development of improved
immunosuppressive therapies, which have led to a concomitant decrease in cardiac …

The studies were undertaken to evaluate feasibility of pulmonary delivery of liposomaly
encapsulated tacrolimus dry powder inhaler for prolonged drug retention in lungs as rescue …

Immunosuppression remains the mainstay of therapy for successful outcomes after lung
transplantation. The need for optimal immunosuppression became evident to maintain long …

Clinical and mechanistic differences between FK506 (tacrolimus) and cyclosporin A | Nephrology
Dialysis Transplantation | Oxford Academic Skip to Main Content Advertisement intended for …

Adoptive transfer of autologous Epstein-Barr virus–specific cytotoxic T lymphocytes (EBV-
CTLs) to solid organ transplant (SOT) recipients has been shown safe and effective for the …

OBJECTIVE: A retrospective study involving 13 institutions was performed to assess the
efficacy of conversion from cyclosporine (INN: ciclosporin) to tacrolimus. METHODS: Data …

Peptidyl-prolyl isomerase (PPIase) catalyzes the interconversion of a specific Pro-imide
bond between the cis and trans conformations. Two families of PPIases, cyclophilins and …