Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

Epigenetic inheritance is a phenomenon whereby stochastic or signal-induced changes to
parental germline epigenome modulate phenotypic output in one or more subsequent …

Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

Our efforts to understand the developmental origins of birth defects and disease have
primarily focused on maternal exposures and intrauterine stressors. Recently, research into …

Exposing a male rat to an obesogenic high-fat diet (HFD) influences attractiveness to
potential female mates, the subsequent interaction of female mates with infant offspring, and …

Background: The organochlorine dichlorodiphenyltrichloroethane (DDT) is banned
worldwide owing to its negative health effects. It is exceptionally used as an insecticide for …

Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …

Recent evidence in humans and animals indicates an association between maternal obesity
and offspring behavioral outcomes. In humans, increased maternal body mass index has …

Emerging research suggests that exposures occurring years before conception are
important determinants of the health of future offspring and subsequent generations …