Designing hydrogels for controlled drug delivery
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
pH sensitive hydrogels in drug delivery: Brief history, properties, swelling, and release mechanism, material selection and applications
Improving the safety efficacy ratio of existing drugs is a current challenge to be addressed
rather than the development of novel drugs which involve much expense and time. The …
rather than the development of novel drugs which involve much expense and time. The …
Bioinspired Spatiotemporal Management toward RNA Therapies
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …
intervention, especially with some that have been approved by the FDA such as the mRNA …
Bio-inspired engineering of cell-and virus-like nanoparticles for drug delivery
The engineering of future generations of nanodelivery systems aims at the creation of
multifunctional vectors endowed with improved circulation, enhanced targeting and …
multifunctional vectors endowed with improved circulation, enhanced targeting and …
Strategic design of intelligent-responsive nanogel carriers for cancer therapy
Owing to the distinctive constituents of tumor tissue from those healthy organs,
nanomedicine strategies show significant potentials in smart drug delivery. Nowadays …
nanomedicine strategies show significant potentials in smart drug delivery. Nowadays …
Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting
X Fu, Y Shi, T Qi, S Qiu, Y Huang, X Zhao… - Signal transduction and …, 2020 - nature.com
Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …
Recent developments in stimuli-responsive polymer nanogels for drug delivery and diagnostics: A review
NK Preman, RR Barki, A Vijayan, SG Sanjeeva… - European Journal of …, 2020 - Elsevier
Polymer nanogels (NGs) are water-swellable, cross-linked 3D network structures with size
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …
In situ onepot synthesis of MOF–polydopamine hybrid nanogels with enhanced photothermal effect for targeted cancer therapy
Herein, a simple onepot way is designed to prepare a type of multifunctional metal–organic
framework (MOF)based hybrid nanogels by in situ hybridization of dopamine monomer in …
framework (MOF)based hybrid nanogels by in situ hybridization of dopamine monomer in …
Nanogels for intracellular delivery of biotherapeutics
D Li, CF van Nostrum, E Mastrobattista… - Journal of Controlled …, 2017 - Elsevier
Many biomolecules, such as proteins and genes, are presently used as therapeutics.
However, their delivery to target sites inside cells is challenging because of their large …
However, their delivery to target sites inside cells is challenging because of their large …
Recent advances in CXCL12/CXCR4 antagonists and nano-based drug delivery systems for cancer therapy
R Zhao, J Liu, Z Li, W Zhang, F Wang, B Zhang - Pharmaceutics, 2022 - mdpi.com
Chemokines can induce chemotactic cell migration by interacting with G protein-coupled
receptors to play a significant regulatory role in the development of cancer. CXC chemokine …
receptors to play a significant regulatory role in the development of cancer. CXC chemokine …