Heterochromatin revisited

SIS Grewal, S Jia - Nature Reviews Genetics, 2007 - nature.com
The formation of heterochromatin, which requires methylation of histone H3 at lysine 9 and
the subsequent recruitment of chromodomain proteins such as heterochromatin protein …

The epigenetics of rRNA genes: from molecular to chromosome biology

B McStay, I Grummt - Annual review of cell and developmental …, 2008 - annualreviews.org
In eukaryotes, the genes encoding ribosomal RNAs (rDNA) exist in two distinct epigenetic
states that can be distinguished by a specific chromatin structure that is maintained …

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

JR Whetstine, A Nottke, F Lan, M Huarte, S Smolikov… - Cell, 2006 - cell.com
Histone methylation regulates chromatin structure, transcription, and epigenetic state of the
cell. Histone methylation is dynamically regulated by histone methylases and demethylases …

Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin

CR Vakoc, SA Mandat, BA Olenchock, GA Blobel - Molecular cell, 2005 - cell.com
Methylation of histones modulates chromatin structure and function. Whereas methylation of
histone H3 on lysines 4, 36, and 79 has been linked with gene activation, methylation of H3 …

From silencing to gene expression: real-time analysis in single cells

SM Janicki, T Tsukamoto, SE Salghetti, WP Tansey… - Cell, 2004 - cell.com
We have developed an inducible system to visualize gene expression at the levels of DNA,
RNA and protein in living cells. The system is composed of a 200 copy transgene array …

Role of protein methylation in regulation of transcription

DY Lee, C Teyssier, BD Strahl, MR Stallcup - Endocrine reviews, 2005 - academic.oup.com
In the last few years, the discovery of lysine and arginine methylation in histones and other
proteins and the enzymes that carry out these posttranslational modifications has added a …

Histone variants: deviants?

RT Kamakaka, S Biggins - Genes & development, 2005 - genesdev.cshlp.org
Histones are a major component of chromatin, the protein-DNA complex fundamental to
genome packaging, function, and regulation. A fraction of histones are nonallelic variants …

Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons

V Saint-André, E Batsché, C Rachez… - Nature structural & …, 2011 - nature.com
Pre-messenger RNAs (pre-mRNAs) maturation is initiated cotranscriptionally. It is therefore
conceivable that chromatin-borne information participates in alternative splicing. Here we …

Epigenetic modifications and plant hormone action

C Yamamuro, JK Zhu, Z Yang - Molecular plant, 2016 - cell.com
The action of phytohormones in plants requires the spatiotemporal regulation of their
accumulation and responses at various levels. Recent studies reveal an emerging …

Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

C Flueck, R Bartfai, J Volz, I Niederwieser… - PLoS …, 2009 - journals.plos.org
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …