Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …

Mycobacterium tuberculosis remains a major public health burden. It is generally thought
that while B cell-and antibody-mediated immunity plays an important role in host defense …

Mycobacterium tuberculosis (Mtb) infection is a major international public health problem.
One‐third of the world′ s population is thought to have latent tuberculosis, a condition …

Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million
new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …

Extensive work illustrating the importance of cellular immune mechanisms for protection
against Mycobacterium tuberculosis has largely relegated B‐cell biology to an afterthought …

There is an urgent need for new and better vaccines against tuberculosis (TB). Current
vaccine design strategies are generally focused on the enhancement of cell-mediated …

Background. The relevance of antibodies (Abs) in the defense against Mycobacterium
tuberculosis infection remains uncertain. We investigated the role of Abs to the …

Fifty years after the introduction of the first effective antimicrobial agents against
Mycobacterium tuberculosis, this pathogen continues to be a tremendous public health …

We investigated the ability of human antibodies induced by Mycobacterium bovis bacillus
Calmette-Guérin (BCG) vaccination to protect against mycobacterial infections. Serum …