The safety of propofol versus sevoflurane for general anesthesia in children: a meta-analysis of randomized controlled trials

Y Zhao, F Qin, Y Liu, Y Dai, X Cen - Frontiers in Surgery, 2022 - frontiersin.org
Background Propofol and sevoflurane are the most used anesthetics for pediatric surgery.
Emergence agitation, postoperative nausea and vomiting and postoperative pain are the …

Recent advances in our understanding of neurodevelopmental outcomes in congenital heart disease

BR White, LS Rogers, MP Kirschen - Current opinion in pediatrics, 2019 - journals.lww.com
Although many risk factors in CHD are not modifiable, there is promise for interventions to
improve neurodevelopmental outcomes in patients with CHD. Biomarkers are needed to …

Magnetic controlled growth rods in the treatment of scoliosis: safety, efficacy and patient selection

AI Tsirikos, SB Roberts - Medical Devices: Evidence and Research, 2020 - Taylor & Francis
Early-onset scoliosis is defined as a spinal curvature greater than 10° in children prior to 10
years of age. Untreated EOS may lead to progressively severe spinal deformity, impaired …

Multiple general anesthesia in children: a systematic review of its effect on neurodevelopment

G Colletti, M Di Bartolomeo, S Negrello… - Journal of Personalized …, 2023 - mdpi.com
The effect of multiple general anesthesia (mGA) procedures administered in early life is a
critical theme and has led the Food and Drug Administration (FDA) to issue an alert. This …

Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in …

J Wan, L Ma, X Jiao, W Dong, J Lin… - CNS Neuroscience …, 2024 - Wiley Online Library
Aim Repeated exposure to ketamine during the neonatal period in mice leads to cognitive
impairments in adulthood. These impairments are likely caused by synaptic plasticity and …

Metallosis is commonly associated with magnetically controlled growing rods; results from an independent multicentre explant database

PRP Rushton, SL Smith, D Fender, AJ Bowey… - European Spine …, 2021 - Springer
Purpose Determine the incidence of metallosis around MAGEC rods. Methods A multicentre
explant database was searched to identify cases with complete intraoperative findings at rod …

Development of a primate model to evaluate the effects of ketamine and surgical stress on the neonatal brain

C Wang, A Bhutta, X Zhang, F Liu… - Experimental …, 2023 - journals.sagepub.com
With advances in pediatric and obstetric surgery, pediatric patients are subject to complex
procedures under general anesthesia. The effects of anesthetic exposure on the developing …

Global burn registry perspective on head and neck burns

LM Ngaage, MR Borrelli, JA Rose… - Annals of plastic …, 2021 - journals.lww.com
Methods We conducted an epidemiological study of all head and neck burns in 14 countries
reported in the World Health Organization Global Burn Registry. Multivariate regression was …

[HTML][HTML] Unraveling the signaling network between dysregulated microRNA and mRNA expression in sevoflurane-induced developmental neurotoxicity in rat

Y Wang, X Men, X Huang, X Qiu, W Wang, J Zhou… - Heliyon, 2024 - cell.com
Research has indicated that general anesthesia may cause neuroapoptosis and long-term
cognitive dysfunction in developing animals, however, the precise mechanisms …

Comparison of surgical outcomes between bioabsorbable and metal screw fixation for distal tibial physeal fracture in children and adolescent

WS Kim, MJ Oh, MS Park, KH Sung - International Orthopaedics, 2024 - Springer
Purpose This study aimed to compare the surgical outcomes between bioabsorbable and
metal screw fixation for distal tibial physeal fracture in children and adolescents …