The vertebrate retina develops from a specified group of precursor cells that adopt distinct
identities and generate lineages of either the neural retina, retinal pigmented epithelium, or …

The evolutionary and genetic origins of the specialized body plan of flatfish are largely
unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 …

The emergence of retinal progenitor cells and differentiation to various retinal cell types
represent fundamental processes during retinal development. Herein, we provide a …

The zebrafish is an invaluable model organism for genetic, developmental, and disease
research. Although its high conservation with humans is often cited as justification for its use …

Molecular information on the early stages of human retinal development remains scarce due
to limitations in obtaining early human eye samples. Pluripotent stem cell-derived retinal …

A central goal of adult neurogenesis research is to characterize the cellular constituents of a
neurogenic niche and to understand how these cells regulate the production of new …

The visceral ganglion (VG) comprises the basic motor pool of the swimming ascidian
tadpole and has been proposed to be homologous to the spinal cord of vertebrates. Here …

The motor ganglion (MG) controls the rhythmic swimming behavior of the Ciona intestinalis
tadpole. Despite its cellular simplicity (five pairs of neurons), the MG exhibits conservation of …

Vision depends on accurate signal conduction from the retina to the brain through the optic
nerve, an important part of the central nervous system that consists of bundles of axons …

Rhodopsin (rh1) is the visual pigment expressed in rod photoreceptors of vertebrates that is
responsible for initiating the critical first step of dim-light vision. Rhodopsin is usually a single …