The release of extracellular vesicles (EV) by the syncytiotrophoblast (STB) may be an
important mechanism by which the placenta signals to the mother. STB derived EV (STBEV) …

The human placenta is an anatomically unique structure that extrudes a variety of
extracellular vesicles into the maternal blood (including syncytial nuclear aggregates …

Preeclampsia is a unique multiple system disorder that affects 5% to 8% of pregnancies.
Exosomes, membrane-encapsulated vesicles that are released into the extracellular …

Background Failure of physiologic transformation of spiral arteries has been reported in
preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact …

Background Hydroxychloroquine (HCQ) is regarded as a mainstay in the treatment of
systemic lupus erythematosus (SLE) because of its efficacy in preventing flares, achieving …

During the pregnancy associated syndrome preeclampsia (PE), there is increased release
of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin …

STUDY QUESTION What proteins are carried by extracellular vesicles (EVs) released from
normal first trimester placentae? SUMMARY ANSWER One thousand five hundred and …

Background Preeclampsia (PE), characterized by hypertension and proteinuria, is a leading
cause of perinatal and maternal mortality. Considering that mutation of H19 gene is closely …

Innate and adaptive immune involvement in hemolysis, elevated liver enzymes and low
platelet (HELLP) syndrome is an understudied field, although it is of high clinical importance …

Intercellular communication is a critical process in biological mechanisms. During
pregnancy foetoplacental tissues release a heterogeneous group of extracellular vesicles …