Understanding the formation of the complex nervous system hinges on decoding the
mechanism that specifies a vast array of neuronal types, each endowed with a unique …

Amacrine cells (ACs) are a diverse class of interneurons that modulate input from
photoreceptors to retinal ganglion cells (RGCs), rendering each RGC type selectively …

The visual signal processing in the retina requires the precise organization of diverse
neuronal types working in concert. While single-cell omics studies have identified more than …

Nicotinic acetylcholine receptors (nAChRs) play crucial roles in various human disorders,
with the α7, α4, α6, and α3-containing nAChR subtypes extensively studied in relation to …

A fundamental organizing plan of the retina is that visual information is divided into ON and
OFF streams that are processed in separate layers. This functional dichotomy originates in …

Bipolar cells (BCs) are integral to the retinal circuits that extract diverse features from the
visual environment. They bridge photoreceptors to ganglion cells, the source of retinal …

Neural computations arise from highly precise connections between specific types of
neurons. Retinal ganglion cells (RGCs) with similar stratification patterns are positioned to …

Despite known single-cell expression profiles in vertebrate retinas, understanding of their
developmental and evolutionary expression patterns among homologous cell classes …

Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cellular
heterogeneity by characterizing cell types across tissues and species. While several mouse …

Astrocytes throughout the central nervous system are heterogeneous in both structure and
function. This diversity leads to tissue‐specific specialization where morphology is adapted …