Fatty acid transport and signaling: mechanisms and physiological implications

D Samovski, M Jacome-Sosa… - Annual review of …, 2023 - annualreviews.org
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel
source and also serve as metabolic regulators through FA signaling mediated by membrane …

CD36 favours fat sensing and transport to govern lipid metabolism

Y Li, X Huang, G Yang, K Xu, Y Yin, G Brecchia… - Progress in lipid …, 2022 - Elsevier
CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a
critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 …

Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism

MY Pepino, O Kuda, D Samovski… - Annual review of …, 2014 - annualreviews.org
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …

Metabolic effects of non-nutritive sweeteners

MY Pepino - Physiology & behavior, 2015 - Elsevier
Until recently, the general belief was that non-nutritive sweeteners (NNSs) were healthy
sugar substitutes because they provide sweet taste without calories or glycemic effects …

Taste of fat: a sixth taste modality?

P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …

Complex pharmacology of free fatty acid receptors

G Milligan, B Shimpukade, T Ulven… - Chemical …, 2017 - ACS Publications
G protein-coupled receptors (GPCRs) are historically the most successful family of drug
targets. In recent times it has become clear that the pharmacology of these receptors is far …

Physiology of the tongue with emphasis on taste transduction

ME Doyle, HU Premathilake, Q Yao… - Physiological …, 2023 - journals.physiology.org
The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Exogenous lipids promote the growth of breast cancer cells via CD36

J Zhao, Z Zhi, C Wang, H Xing, G Song… - Oncology …, 2017 - spandidos-publications.com
Cancer cells present sustained de novo fatty acid (FA) synthesis with increased production
of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs). This change in FA …

The role of SNMPs in insect olfaction

S Cassau, J Krieger - Cell and Tissue Research, 2021 - Springer
The sense of smell enables insects to recognize olfactory signals crucial for survival and
reproduction. In insects, odorant detection highly depends on the interplay of distinct …

[HTML][HTML] Mechanism of fat taste perception: Association with diet and obesity

D Liu, N Archer, K Duesing, G Hannan, R Keast - Progress in lipid research, 2016 - Elsevier
Energy homeostasis plays a significant role in food consumption and body weight regulation
with fat intake being an area of particular interest due to its palatability and high energy …