Abstract Melatonin (N-acetyl-5-methoxytryptamine) has revealed itself as an ubiquitously
distributed and functionally diverse molecule. The mechanisms that control its synthesis …

A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant
pineal secretory product, has oncostatic properties in a wide variety of tumors and …

Light exposure during the night is becoming progressively more common throughout the
world, particularly in areas where electricity is commonly used. Also, the availability of …

This review article discusses recent work on the melatonin‐mediated circadian regulation
and integration of molecular, dietary, and metabolic signaling mechanisms involved in …

The authors have shown that, via activation of its MT1 receptor, melatonin modulates the
transcriptional activity of various nuclear receptors and the proliferation of both ERα+ and …

Humans are diurnal organisms whose biological clock and temporal organization depend
on natural light/dark cycles. Throughout evolution, changes in the photoperiod were a signal …

Melatonin has significant inhibitory effects in numerous cancers, especially breast cancer. In
estrogen receptor (ER)-positive human breast cancer, the oncostatic actions of melatonin …

G protein-coupled receptors are key regulators of cellular communication, mediating the
efficient coordination of a cell's responses to extracellular stimuli. When stimulated these …