Loss of consciousness and righting reflex following traumatic brain injury: predictors of post-injury symptom development (a narrative review)

R Berman, H Spencer, M Boese, S Kim, K Radford… - Brain sciences, 2023 - mdpi.com
Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …

Does the model reflect the system? When two-dimensional biomechanics is not 'good enough'

AL Smith, J Davis… - Journal of the …, 2023 - royalsocietypublishing.org
Models are mathematical representations of systems, processes or phenomena. In
biomechanics, finite-element modelling (FEM) can be a powerful tool, allowing biologists to …

A roadmap of brain recovery in a mouse model of concussion: insights from neuroimaging

XV To, FA Nasrallah - Acta neuropathologica communications, 2021 - Springer
Concussion or mild traumatic brain injury is the most common form of traumatic brain injury
with potentially long-term consequences. Current objective diagnosis and treatment options …

A cross-comparative analysis of in vivo versus ex vivo MRI indices in a mouse model of concussion

XV To, ND Kurniawan, P Cumming, FA Nasrallah - Brain research, 2023 - Elsevier
Background We present a cross-sectional, case-matched, and pair-wise comparison of
structural magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), and neurite …

Amide proton transfer-weighted magnetic resonance imaging for detecting severity and predicting outcome after traumatic brain injury in rats

Y Dong, Y Gu, J Lu, J Wan, S Jiang… - Neurotrauma …, 2022 - liebertpub.com
After traumatic brain injury (TBI), early assessment of secondary injury severity is critically
important for estimating prognosis and treatment stratification. Currently, secondary injury …

Neurite orientation dispersion and density imaging in a rodent model of acute mild traumatic brain injury

P McCunn, X Xu, A Moszczynski, A Li… - Journal of …, 2021 - Wiley Online Library
ABSTRACT Background and Purpose Identification of changesin brain microstructure
following mild traumatic brain injury (mTBI) could be instrumental in understanding the …

Multi-modal magnetic resonance imaging in a mouse model of concussion

XV To, FA Nasrallah - Scientific Data, 2021 - nature.com
This data collection contains Magnetic Resonance Imaging (MRI) data, including structural,
diffusion, stimulus-evoked, and resting-state functional MRI and behavioural assessment …

Diffusion tensor imaging detects acute pathology-specific changes in the P301L tauopathy mouse model following traumatic brain injury

N Soni, R Medeiros, K Alateeq, XV To… - Frontiers in …, 2021 - frontiersin.org
Traumatic brain injury (TBI) has been linked with tauopathy. However, imaging methods that
can non-invasively detect tau-protein abnormalities following TBI need further investigation …

Hippocampal demyelination is associated with increased magnetic susceptibility in a mouse model of concussion

XV To, V Vegh, N Owusu-Amoah, P Cumming… - Experimental …, 2023 - Elsevier
Structural and functional deficits in the hippocampus are a prominent feature of moderate-
severe traumatic brain injury (TBI). In this work, we investigated the potential of Quantitative …

Microstructural MRI Evolution During Adult Mouse Brain Maturation and Concussion Recovery

N Rahman - 2024 - search.proquest.com
Mild traumatic brain injury (mTBI), also called concussion, has become a significant public
health concern. Current clinical neuroimaging techniques lack the sensitivity and specificity …