Periodontal microbiology and microbial etiology of periodontal diseases: historical concepts and contemporary perspectives

GN Belibasakis, D Belstrøm, S Eick… - Periodontology …, 2023 - Wiley Online Library
This narrative review summarizes the collective knowledge on periodontal microbiology,
through a historical timeline that highlights the European contribution in the global field. The …

Adjunctive effect of systemic antimicrobials in periodontitis therapy: A systematic review and meta‐analysis

W Teughels, M Feres, V Oud, C Martín… - Journal of Clinical …, 2020 - Wiley Online Library
Aim To answer the following PICOS questions: in patients with periodontitis, which is the
efficacy of adjunctive systemic antimicrobials, in comparison with subgingival debridement …

Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis

K Jepsen, S Jepsen - Periodontology 2000, 2016 - Wiley Online Library
This review gives an update of the current scientific evidence on the efficacy of the
adjunctive use of systemic and local antibiotics/antimicrobials in the treatment of …

Surgical and nonsurgical periodontal therapy. Learned and unlearned concepts

LJA Heitz‐Mayfield, NP Lang - Periodontology 2000, 2013 - Wiley Online Library
This review aims to highlight concepts relating to nonsurgical and surgical periodontal
therapy, which have been learned and unlearned over the past few decades. A number of …

Lessons learned and unlearned in periodontal microbiology

R Teles, F Teles, J Frias‐Lopez, B Paster… - Periodontology …, 2013 - Wiley Online Library
Periodontal diseases are initiated by bacterial species living in polymicrobial biofilms at or
below the gingival margin and progress largely as a result of the inflammation elicited by …

[HTML][HTML] Western and non-western gut microbiomes reveal new roles of Prevotella in carbohydrate metabolism and mouth–gut axis

V Prasoodanan PK, AK Sharma, S Mahajan… - npj Biofilms and …, 2021 - nature.com
The abundance and diversity of host-associated Prevotella species have a profound impact
on human health. To investigate the composition, diversity, and functional roles of Prevotella …

Antibiotic resistance in human chronic periodontitis microbiota

TE Rams, JE Degener… - Journal of …, 2014 - Wiley Online Library
Background: Patients with chronic periodontitis (CP) may yield multiple species of putative
periodontal bacterial pathogens that vary in their antibiotic drug susceptibility. This study …

[HTML][HTML] Mechanisms of action of systemic antibiotics used in periodontal treatment and mechanisms of bacterial resistance to these drugs

GMS Soares, LC Figueiredo, M Faveri… - Journal of applied oral …, 2012 - SciELO Brasil
Antibiotics are important adjuncts in the treatment of infectious diseases, including
periodontitis. The most severe criticisms to the indiscriminate use of these drugs are their …

Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm

D Herrera, B Alonso, R León… - Journal of clinical …, 2008 - Wiley Online Library
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be
efficacious if the biofilm is not disrupted? Can the type of debridement of the subgingival …

Adjunctive benefits of systemic amoxicillin and metronidazole in non‐surgical treatment of generalized aggressive periodontitis: a randomized placebo‐controlled …

A Guerrero, GS Griffiths, L Nibali… - Journal of clinical …, 2005 - Wiley Online Library
Background: The objective of this study was to assess the adjunctive clinical effect of the
administration of systemic amoxicillin and metronidazole in the non‐surgical treatment of …