[HTML][HTML] Microbial production of polyunsaturated fatty acids—high-value ingredients for aquafeed, superfoods, and pharmaceuticals

S Jovanovic, D Dietrich, J Becker, M Kohlstedt… - Current opinion in …, 2021 - Elsevier
Highlights•PUFAs are applied worldwide in superfoods, aquafeed and pharmaceuticals.•
Climate warming and declining fishery cause a severe supply and demand gap.•The PUFAs …

CRISPR/Cas9-based genome editing of the filamentous fungi: the state of the art

TQ Shi, GN Liu, RY Ji, K Shi, P Song, LJ Ren… - Applied microbiology …, 2017 - Springer
In recent years, a variety of genetic tools have been developed and applied to various
filamentous fungi, which are widely applied in agriculture and the food industry. However …

Microbial sources of polyunsaturated fatty acids (PUFAs) and the prospect of organic residues and wastes as growth media for PUFA-producing microorganisms

M Kothri, M Mavrommati, AM Elazzazy… - FEMS Microbiology …, 2020 - academic.oup.com
The discovery of non-fish sources of polyunsaturated fatty acids (PUFAs) is of great
biotechnological importance. Although various oleaginous microalgae and fungi are able of …

[HTML][HTML] Microbes: a hidden treasure of polyunsaturated fatty acids

AM Shah, W Yang, H Mohamed, Y Zhang… - Frontiers in Nutrition, 2022 - frontiersin.org
Microbes have gained a lot of attention for their potential in producing polyunsaturated fatty
acids (PUFAs). PUFAs are gaining scientific interest due to their important health-promoting …

[HTML][HTML] Production, biosynthesis, and commercial applications of fatty acids from oleaginous fungi

XY Zhang, B Li, BC Huang, FB Wang, YQ Zhang… - Frontiers in …, 2022 - frontiersin.org
Oleaginous fungi (including fungus-like protists) are attractive in lipid production due to their
short growth cycle, large biomass and high yield of lipids. Some typical oleaginous fungi …

Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

J Wang, X Yu, K Wang, L Lin, HH Liu… - Bioresource …, 2023 - Elsevier
Omega-6 polyunsaturated fatty acids (ω6-PUFAs), such as γ-linolenic acid (GLA), dihomo-γ-
linolenic acid (DGLA) and arachidonic acid (ARA), are indispensable nutrients for human …

Filamentous fungi for sustainable vegan food production systems within a circular economy: Present status and future prospects

MK Awasthi, V Kumar, C Hellwig, R Wikandari… - Food Research …, 2023 - Elsevier
Filamentous fungi serve as potential candidates in the production of different value-added
products. In the context of food, there are several advantages of using filamentous fungi for …

[HTML][HTML] Mucor circinelloides: a model organism for oleaginous fungi and its potential applications in bioactive lipid production

ABA Fazili, AM Shah, X Zan, T Naz, S Nosheen… - Microbial cell …, 2022 - Springer
Microbial oils have gained massive attention because of their significant role in industrial
applications. Currently plants and animals are the chief sources of medically and …

[HTML][HTML] The potential of single-cell oils derived from filamentous fungi as alternative feedstock sources for biodiesel production

SI Mhlongo, OT Ezeokoli, A Roopnarain… - Frontiers in …, 2021 - frontiersin.org
Microbial lipids, also known as single-cell oils (SCOs), are highly attractive feedstocks for
biodiesel production due to their fast production rates, minimal labor requirements …

Deletion of Plasma Membrane Malate Transporters Increased Lipid Accumulation in the Oleaginous Fungus Mucor circinelloides WJ11

J Yang, JT Cánovas-Márquez, P Li, S Li… - Journal of agricultural …, 2021 - ACS Publications
Malate as an important intermediate metabolite, its subcellular location, and concentration
have a significant impact on fungal lipid metabolism. Previous studies showed that the …