SARS-CoV-2 pathogenesis
MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …
Understanding COVID-19-associated coagulopathy
EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19
A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—a new coronavirus that
has led to a worldwide pandemic—has a furin cleavage site (PRRAR) in its spike protein …
has led to a worldwide pandemic—has a furin cleavage site (PRRAR) in its spike protein …
Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study
Background An important feature of severe acute respiratory syndrome coronavirus 2
pathogenesis is COVID-19-associated coagulopathy, characterised by increased thrombotic …
pathogenesis is COVID-19-associated coagulopathy, characterised by increased thrombotic …
A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
[HTML][HTML] High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study
J Helms, C Tacquard, F Severac, I Leonard-Lorant… - Intensive care …, 2020 - Springer
Purpose Little evidence of increased thrombotic risk is available in COVID-19 patients. Our
purpose was to assess thrombotic risk in severe forms of SARS-CoV-2 infection. Methods All …
purpose was to assess thrombotic risk in severe forms of SARS-CoV-2 infection. Methods All …
Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past
Abstract Coronavirus disease 2019 (COVID-19) or severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), a novel coronavirus strain disease, has recently emerged in …
coronavirus 2 (SARS-CoV-2), a novel coronavirus strain disease, has recently emerged in …
Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia
N Tang, D Li, X Wang, Z Sun - Journal of thrombosis and …, 2020 - Wiley Online Library
Background In the recent outbreak of novel coronavirus infection in Wuhan, China,
significantly abnormal coagulation parameters in severe novel coronavirus pneumonia …
significantly abnormal coagulation parameters in severe novel coronavirus pneumonia …
Coagulopathy of coronavirus disease 2019
Objectives: Recent studies have reported a high prevalence of thrombotic events in
coronavirus disease 2019. However, the significance of thromboembolic complications has …
coronavirus disease 2019. However, the significance of thromboembolic complications has …