Evidence-based management has improved long-term survival in patients with heart failure
(HF). However, an unintended consequence of increased longevity is that patients with HF …

Background Breathlessness is a common and disabling symptom which affects many
people with advanced cardiorespiratory disease and cancer. The most effective treatments …

Background: This document provides clinical recommendations for the pharmacologic
treatment of chronic obstructive pulmonary disease (COPD). It represents a collaborative …

Since the inception of the Canadian Cardiovascular Society heart failure (HF) guidelines in
2006, much has changed in the care for patients with HF. Over the past decade, the HF …

Background: Dyspnea is a common, distressing symptom of cardiopulmonary and
neuromuscular diseases. Since the ATS published a consensus statement on dyspnea in …

Refer all patients with a chest X-ray suggestive of MPM urgently (via the 2-week wait
suspected cancer pathway in England and Wales). Consider referral for further investigation …

Respiratory depression limits the use of opioid analgesia. Although well described clinically,
the specific mechanisms of opioid action on respiratory control centres in the brain have …

Pulmonary hypertension remained an unexplained intractable disease with poor prognosis.
In the last 2 decades, however, the diagnosis and treatment methods for this disease …

Background Palliative oxygen therapy is widely used for treatment of dyspnoea in
individuals with life-limiting illness who are ineligible for long-term oxygen therapy. We …

Objective To evaluate the safety of benzodiazepines and opioids in patients with very severe
chronic obstructive pulmonary disease (COPD). Design Population based longitudinal …