Telomeres protect the ends of chromosomes but shorten following cell division in the
absence of telomerase activity. When telomeres become critically short or damaged, a DNA …

While genomic alterations are fundamental to biological evolution, enabling adaptation and
diversity, they can also result in detrimental outcomes, such as the development of genetic …

Telomeres are the protective nucleoprotein structures at the end of linear eukaryotic
chromosomes. Telomeres' repetitive nature and length have traditionally challenged the …

The human telomere system is highly dynamic. Both short and long leucocyte average
telomere lengths (aTL) are associated with an increased risk of cancer and early death …

Research into aging constitutes a pivotal endeavor aimed at elucidating the underlying
biological mechanisms governing aging and age-associated diseases, as well as promoting …

Telomerase, crucial for maintaining telomere length, is an attractive target for cancer therapy
due to its role in cellular immortality. Despite three decades of research efforts, no small …

Disease categories traditionally reflect a historical clustering of clinical phenotypes based on
biologic and nonbiologic features. Multiomics approaches have striven to identify signatures …

Telomeres are protective structures at the end of eukaryotic chromosomes that are strongly
implicated in ageing and ill health. They attrition upon every cellular reproductive cycle …

Background Previous researches have demonstrated an association between carotenoids
and elongated telomeres. Nonetheless, there is scant scientific evidence examining this …

Biological information is encoded in a sequence of biochemical molecules such as nucleic
acids and amino acids, and nanopore sequencing is a long-read sequencing technology …