Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …
Nanomedicine in treatment of breast cancer–A challenge to conventional therapy
M Afzal, KS Alharbi, NK Alruwaili, FA Al-Abassi… - Seminars in cancer …, 2021 - Elsevier
Amongst the various types of cancer, breast cancer is a highly heterogeneous disease and
known as the leading cause of death among women globally. The extensive interdisciplinary …
known as the leading cause of death among women globally. The extensive interdisciplinary …
[HTML][HTML] Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics
PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …
expected to continue to affect the population in forthcoming years. Additionally, treatment …
Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment
M Zhang, H Jiang, L Wu, H Lu, H Bera, X Zhao… - Journal of Controlled …, 2022 - Elsevier
With specific and inherent mRNA cleaving activity, small interfering RNA (siRNA) has been
deemed promising therapeutics to reduce the exacerbation rate of asthma by inhibiting the …
deemed promising therapeutics to reduce the exacerbation rate of asthma by inhibiting the …
Receptor-based targeting of engineered nanocarrier against solid tumors: Recent progress and challenges ahead
Background In past few decades, the research on engineered nanocarriers (NCs) has
gained significant attention in cancer therapy due to selective delivery of drug molecules on …
gained significant attention in cancer therapy due to selective delivery of drug molecules on …
Lipid/polymer-based nanocomplexes in nucleic acid delivery as cancer vaccines
S Beg, WH Almalki, F Khatoon, KS Alharbi… - Drug Discovery …, 2021 - Elsevier
Highlights•Cancer vaccines present new therapeutic interventions for treatment.•Use of
functional lipids and polymers provides enhanced deliverability.•Significant momentum has …
functional lipids and polymers provides enhanced deliverability.•Significant momentum has …
Recent advances in liposome-based targeted cancer therapy
Nano-drug delivery systems have opened new pathways for tumor treatment by overcoming
some of the limitations of conventional drugs, such as physiological degradation, short half …
some of the limitations of conventional drugs, such as physiological degradation, short half …
[HTML][HTML] Peptide-assembled nanoparticles targeting tumor cells and tumor microenvironment for cancer therapy
M Zhang, H Xu - Frontiers in Chemistry, 2023 - frontiersin.org
Tumor cells and corrupt stromal cells in the tumor microenvironment usually overexpress
cancer-specific markers that are absent or barely detectable in normal cells, providing …
cancer-specific markers that are absent or barely detectable in normal cells, providing …
[HTML][HTML] Investigating the role of peptides in effective therapies against cancer
R Naeimi, A Bahmani, S Afshar - Cancer Cell International, 2022 - Springer
Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat
cancer effectively and to overcome these challenges, fundamental innovations in traditional …
cancer effectively and to overcome these challenges, fundamental innovations in traditional …
Serine O-acetyltransferase derived NV14 peptide reduces cytotoxicity in H2O2 induced MDCK cells and inhibits MCF-7 cell proliferation through caspase gene …
Background Most of the bioactive peptides exhibit antioxidant effect and do elicit inhibitory
effect on proliferation of cancer cells. This study investigates the in-vitro antioxidant and anti …
effect on proliferation of cancer cells. This study investigates the in-vitro antioxidant and anti …