Dual-targeting and stimuli-triggered liposomal drug delivery in cancer treatment

N AlSawaftah, WG Pitt, GA Husseini - ACS pharmacology & …, 2021 - ACS Publications
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …

Nanomedicine in treatment of breast cancer–A challenge to conventional therapy

M Afzal, KS Alharbi, NK Alruwaili, FA Al-Abassi… - Seminars in cancer …, 2021 - Elsevier
Amongst the various types of cancer, breast cancer is a highly heterogeneous disease and
known as the leading cause of death among women globally. The extensive interdisciplinary …

[HTML][HTML] Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics

PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …

Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment

M Zhang, H Jiang, L Wu, H Lu, H Bera, X Zhao… - Journal of Controlled …, 2022 - Elsevier
With specific and inherent mRNA cleaving activity, small interfering RNA (siRNA) has been
deemed promising therapeutics to reduce the exacerbation rate of asthma by inhibiting the …

Receptor-based targeting of engineered nanocarrier against solid tumors: Recent progress and challenges ahead

MH Akhter, S Beg, M Tarique, A Malik, S Afaq… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background In past few decades, the research on engineered nanocarriers (NCs) has
gained significant attention in cancer therapy due to selective delivery of drug molecules on …

Lipid/polymer-based nanocomplexes in nucleic acid delivery as cancer vaccines

S Beg, WH Almalki, F Khatoon, KS Alharbi… - Drug Discovery …, 2021 - Elsevier
Highlights•Cancer vaccines present new therapeutic interventions for treatment.•Use of
functional lipids and polymers provides enhanced deliverability.•Significant momentum has …

Recent advances in liposome-based targeted cancer therapy

Y Fidan, S Mucaj, SS Timur… - Journal of Liposome …, 2023 - Taylor & Francis
Nano-drug delivery systems have opened new pathways for tumor treatment by overcoming
some of the limitations of conventional drugs, such as physiological degradation, short half …

[HTML][HTML] Peptide-assembled nanoparticles targeting tumor cells and tumor microenvironment for cancer therapy

M Zhang, H Xu - Frontiers in Chemistry, 2023 - frontiersin.org
Tumor cells and corrupt stromal cells in the tumor microenvironment usually overexpress
cancer-specific markers that are absent or barely detectable in normal cells, providing …

[HTML][HTML] Investigating the role of peptides in effective therapies against cancer

R Naeimi, A Bahmani, S Afshar - Cancer Cell International, 2022 - Springer
Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat
cancer effectively and to overcome these challenges, fundamental innovations in traditional …

Serine O-acetyltransferase derived NV14 peptide reduces cytotoxicity in H2O2 induced MDCK cells and inhibits MCF-7 cell proliferation through caspase gene …

M Velayutham, B Haridevamuthu, PS Priya… - Molecular Biology …, 2022 - Springer
Background Most of the bioactive peptides exhibit antioxidant effect and do elicit inhibitory
effect on proliferation of cancer cells. This study investigates the in-vitro antioxidant and anti …