Advances in TEER measurements of biological barriers in microphysiological systems

H Nazari, J Shrestha, VY Naei, SR Bazaz… - Biosensors and …, 2023 - Elsevier
Biological barriers are multicellular structures that precisely regulate the transport of ions,
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …

A review of electrical impedance characterization of cells for label-free and real-time assays

HT Ngoc Le, J Kim, J Park, S Cho - BioChip Journal, 2019 - Springer
The aim of this review is to discuss label-free and real-time assays characterizing the
electrical impedance of cells for biomedical and pharmacological applications. Electrical …

Direct and label‐free cell status monitoring of spheroids and microcarriers using microfluidic impedance cytometry

L Gong, C Petchakup, P Shi, PL Tan, LP Tan, CY Tay… - Small, 2021 - Wiley Online Library
Abstract 3D cellular spheroids/microcarriers (100 µm–1 mm) are widely used in
biomanufacturing, and non‐invasive biosensors are useful to monitor cell quality in …

Applications of bioimpedance measurement techniques in tissue engineering

M Amini, J Hisdal, H Kalvøy - Journal of Electrical Bioimpedance, 2018 - sciendo.com
Rapid development in the field of tissue engineering necessitates implementation of
monitoring methods for evaluation of the viability and characteristics of the cell cultures in a …

[HTML][HTML] A non-invasive smart scaffold for bone repair and monitoring

Y Huang, L Zhang, Y Ji, H Deng, M Long, S Ge, Y Su… - Bioactive Materials, 2023 - Elsevier
Existing strategies for bone defect repair are difficult to monitor. Smart scaffold materials that
can quantify the efficiency of new bone formation are important for bone regeneration and …

Impedance-based cellular assays for regenerative medicine

W Gamal, H Wu, I Underwood, J Jia… - … of the Royal …, 2018 - royalsocietypublishing.org
Therapies based on regenerative techniques have the potential to radically improve
healthcare in the coming years. As a result, there is an emerging need for non-destructive …

CMOS based whole cell impedance sensing: Challenges and future outlook

A Hedayatipour, S Aslanzadeh, N McFarlane - Biosensors and …, 2019 - Elsevier
With the increasing need for multi-analyte point-of-care diagnosis devices, cell impedance
measurement is a promising technique for integration with other sensing modalities. In this …

Bioelectrochemical applications of microelectrode arrays in cell analysis and engineering

K Ino, H Shiku, T Matsue - Current Opinion in Electrochemistry, 2017 - Elsevier
This review summarizes recent advances in cell-related applications of microelectrode
arrays. In the review, we discuss devices featuring multiple sensors incorporated into a small …

[HTML][HTML] Label-free technology and patient cells: from early drug development to precision medicine

JM Hillger, WL Lieuw, LH Heitman, AP IJzerman - Drug discovery today, 2017 - Elsevier
Highlights•Label-free assays increase biorelevance over traditional label-based
studies.•Patient-derived cells offer increased physiological representability.•Impedance …

Integration of biological systems with electronic-mechanical assemblies

N Yi, H Cui, LG Zhang, H Cheng - Acta biomaterialia, 2019 - Elsevier
Biological systems continuously interact with the surrounding environment because they are
dynamically evolving. The interaction is achieved through mechanical, electrical, chemical …