Cortico-thalamic development and disease: from cells, to circuits, to schizophrenia

MM Angulo Salavarria, C Dell'Amico… - Frontiers in …, 2023 - frontiersin.org
The human brain is the most complex structure generated during development. Unveiling
the ontogenesis and the intrinsic organization of specific neural networks may represent a …

A case for thalamic mechanisms of schizophrenia: perspective from modeling 22q11. 2 deletion syndrome

Y Jiang, MH Patton, SS Zakharenko - Frontiers in Neural Circuits, 2021 - frontiersin.org
Schizophrenia is a severe, chronic psychiatric disorder that devastates the lives of millions of
people worldwide. The disease is characterized by a constellation of symptoms, ranging …

Thalamocortical organoids enable in vitro modeling of 22q11. 2 microdeletion associated with neuropsychiatric disorders

D Shin, CN Kim, J Ross, KM Hennick, SR Wu… - Cell Stem Cell, 2024 - cell.com
Thalamic dysfunction has been implicated in multiple psychiatric disorders. We sought to
study the mechanisms by which abnormalities emerge in the context of the 22q11. 2 …

Structural brain abnormalities in schizophrenia patients with a history and presence of auditory verbal hallucination

M Sone, D Koshiyama, Y Zhu, N Maikusa… - Translational …, 2022 - nature.com
Although many studies have demonstrated structural brain abnormalities associated with
auditory verbal hallucinations (AVH) in schizophrenia, the results remain inconsistent …

Aberrant developmental patterns of gamma-band response and long-range communication disruption in youths with 22q11. 2 deletion syndrome

V Mancini, V Rochas, M Seeber… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Brain oscillations play a pivotal role in synchronizing responses of local and
global ensembles of neurons. Patients with schizophrenia exhibit impairments in oscillatory …

The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder

CJ Weeland, S Kasprzak, NT de Joode, Y Abe… - Translational …, 2022 - nature.com
Larger thalamic volume has been found in children with obsessive-compulsive disorder
(OCD) and children with clinical-level symptoms within the general population. Particular …

[HTML][HTML] Alterations in the volume of thalamic nuclei in patients with schizophrenia and persistent auditory hallucinations

M Perez-Rando, UKA Elvira, G García-Martí… - NeuroImage: Clinical, 2022 - Elsevier
The thalamus is a subcortical structure formed by different nuclei that relay information to the
neocortex. Several reports have already described alterations of this structure in patients of …

[HTML][HTML] Consistently lower volumes across thalamus nuclei in very premature-born adults

M Thalhammer, M Nimpal, J Schulz, V Meedt… - NeuroImage, 2024 - Elsevier
Lasting thalamus volume reduction after preterm birth is a prominent finding. However,
whether thalamic nuclei volumes are affected differentially by preterm birth and whether …

[HTML][HTML] Identifying common and distinct subcortical volumetric abnormalities in 3 major psychiatric disorders: a single-site analysis of 640 participants

PC Tu, WC Chang, MH Chen, JW Hsu… - Journal of psychiatry …, 2022 - ncbi.nlm.nih.gov
Background Subcortical volumetric abnormalities in schizophrenia, bipolar disorder and
major depressive disorder (MDD) have been consistently found on a single-diagnosis basis …

Neuroimaging markers of Alice in Wonderland syndrome in patients with migraine with aura

G Mastria, V Mancini, A Viganò, C Piervincenzi… - Frontiers in …, 2023 - frontiersin.org
Background The Alice in Wonderland syndrome (AIWS) is a transient neurological
disturbance characterized by sensory distortions most frequently associated with migraine in …