Mechanisms of melanocyte death in vitiligo
J Chen, S Li, C Li - Medicinal Research Reviews, 2021 - Wiley Online Library
Vitiligo is an autoimmune depigment disease results from extensive melanocytes
destruction. The destruction of melanocyte is thought to be of multifactorial causation …
destruction. The destruction of melanocyte is thought to be of multifactorial causation …
Regulatory T cells in vitiligo: implications for pathogenesis and therapeutics
M Dwivedi, EH Kemp, NC Laddha, MS Mansuri… - Autoimmunity …, 2015 - Elsevier
Vitiligo is a hypomelanotic autoimmune skin disease arising from a breakdown in
immunological self-tolerance, which leads to aberrant immune responses against …
immunological self-tolerance, which leads to aberrant immune responses against …
CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo
Vitiligo is an autoimmune disease of the skin that results in disfiguring white spots. There are
no US Food and Drug Administration–approved treatments for vitiligo, and most off-label …
no US Food and Drug Administration–approved treatments for vitiligo, and most off-label …
[HTML][HTML] Impaired activation of the Nrf2-ARE signaling pathway undermines H2O2-induced oxidative stress response: a possible mechanism for melanocyte …
Z Jian, K Li, P Song, G Zhu, L Zhu, T Cui, B Liu… - Journal of Investigative …, 2014 - Elsevier
Vitiligo melanocytes possess higher susceptibility to oxidative insults. Consistent with this,
impairment of the antioxidant defense system has been reported to be involved in the onset …
impairment of the antioxidant defense system has been reported to be involved in the onset …
The role of IL-17 in vitiligo: A review
RK Singh, KM Lee, I Vujkovic-Cvijin, D Ucmak… - Autoimmunity …, 2016 - Elsevier
IL-17 is involved in the pathogenesis of several autoimmune diseases; however its role in
vitiligo has not been well defined. Emerging human and mouse studies have demonstrated …
vitiligo has not been well defined. Emerging human and mouse studies have demonstrated …
Vitiligo skin T cells are prone to produce type 1 and type 2 cytokines to induce melanocyte dysfunction and epidermal inflammatory response through Jak signaling
C Martins, L Migayron, C Drullion, C Jacquemin… - Journal of Investigative …, 2022 - Elsevier
Vitiligo is a T cell–mediated inflammatory skin disorder characterized by the loss of
epidermal melanocytes. However, the contribution of melanocytes to the physiopathology of …
epidermal melanocytes. However, the contribution of melanocytes to the physiopathology of …
The many faces of interleukin‐17 in inflammatory skin diseases
R Speeckaert, J Lambert, L Grine… - British Journal of …, 2016 - academic.oup.com
Summary Interleukin (IL)‐17 is an emerging target for inflammatory skin disorders. Given the
remarkable success of its therapeutic inhibition in psoriasis, the pathogenic role of this …
remarkable success of its therapeutic inhibition in psoriasis, the pathogenic role of this …
Predominant role of innate pro-inflammatory cytokines in vitiligo disease
Vitiligo is a skin disorder with melanocyte destruction and an autoimmune basis. Given the
importance of cytokines in autoimmunity, we aimed to find the cytokine profile of innate and …
importance of cytokines in autoimmunity, we aimed to find the cytokine profile of innate and …
Oxidative stress and immune system in vitiligo and thyroid diseases
R Colucci, F Dragoni, S Moretti - Oxidative medicine and …, 2015 - Wiley Online Library
Vitiligo is an acquired dermatological disease frequently associated with autoimmune
thyroid disorders. Several theories have been proposed so far to unravel the complex vitiligo …
thyroid disorders. Several theories have been proposed so far to unravel the complex vitiligo …
Vitiligo-part 1
RG Tarlé, LM Nascimento, MT Mira… - Anais brasileiros de …, 2014 - SciELO Brasil
Vitiligo is a chronic stigmatizing disease, already known for millennia, which mainly affects
melanocytes from epidermis basal layer, leading to the development of hypochromic and …
melanocytes from epidermis basal layer, leading to the development of hypochromic and …