Recent developments in bioprocessing of recombinant proteins: expression hosts and process development
NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …
humans worldwide. The production of therapeutic proteins for treating diseases at large …
Platforms for production of protein-based vaccines: from classical to next-generation strategies
R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …
Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine
Laboratory animal models play an important role in the study of human diseases. Using
appropriate animals is critical not only for basic research but also for the development of …
appropriate animals is critical not only for basic research but also for the development of …
[PDF][PDF] An overview of heterologous expression host systems for the production of recombinant proteins
AR Gomes, SM Byregowda, BM Veeregowda… - Adv. Anim. Vet …, 2016 - academia.edu
With the advent of recombinant DNA technology, cloning and expression of numerous
mammalian genes in different systems have been explored to produce many therapeutics …
mammalian genes in different systems have been explored to produce many therapeutics …
The transgenic animal platform for biopharmaceutical production
LR Bertolini, H Meade, CR Lazzarotto, LT Martins… - Transgenic …, 2016 - Springer
The recombinant production of therapeutic proteins for human diseases is currently the
largest source of innovation in the pharmaceutical industry. The market growth has been the …
largest source of innovation in the pharmaceutical industry. The market growth has been the …
Extranuclear inheritance of mitochondrial genome and epigenetic reprogrammability of chromosomal telomeres in somatic cell cloning of mammals
M Samiec, M Skrzyszowska - International Journal of Molecular Sciences, 2021 - mdpi.com
The effectiveness of somatic cell nuclear transfer (SCNT) in mammals seems to be still
characterized by the disappointingly low rates of cloned embryos, fetuses, and progeny …
characterized by the disappointingly low rates of cloned embryos, fetuses, and progeny …
Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
I Legastelois, S Buffin, I Peubez, C Mignon… - Human vaccines & …, 2017 - Taylor & Francis
The increasing demand for recombinant vaccine antigens or immunotherapeutic molecules
calls into question the universality of current protein expression systems. Vaccine production …
calls into question the universality of current protein expression systems. Vaccine production …
Application of genetically engineered pigs in biomedical research
M Hryhorowicz, D Lipiński, S Hryhorowicz… - Genes, 2020 - mdpi.com
Progress in genetic engineering over the past few decades has made it possible to develop
methods that have led to the production of transgenic animals. The development of …
methods that have led to the production of transgenic animals. The development of …
Goats producing biosimilar human lactoferrin
DM Bogdanovich, VF Radchikov… - … Series: Earth and …, 2021 - iopscience.iop.org
Herd of goats producing biosimilar human lactoferrin has been created. The nature of
transmission of the transgene through a number of generations, productivity according to …
transmission of the transgene through a number of generations, productivity according to …
Current approaches and applications in avian genome editing
Advances in genome-editing technologies and sequencing of animal genomes enable
researchers to generate genome-edited (GE) livestock as valuable animal models that …
researchers to generate genome-edited (GE) livestock as valuable animal models that …