Pathophysiology, emerging techniques for the assessment and novel treatment of aortic stenosis

SM Shah, J Shah, SM Lakey, P Garg, DP Ripley - Open Heart, 2023 - openheart.bmj.com
Our perspectives on aortic stenosis (AS) are changing. Evolving from the traditional thought
of a passive degenerative disease, developing a greater understanding of the condition's …

Management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis

V Tsampasian, C Grafton-Clarke, AEG Ramos… - Open …, 2022 - openheart.bmj.com
Objectives The management of severe aortic stenosis mandates consideration of aortic
valve intervention for symptomatic patients. However, for asymptomatic patients with severe …

Postoperative myocardial fibrosis assessment in aortic valvular heart diseases—a cardiovascular magnetic resonance study

LT Pires, VEE Rosa, TC Morais… - European Heart …, 2023 - academic.oup.com
Aims Left ventricular remodelling occurs during the chronic course of aortic regurgitation
(AR) and aortic stenosis (AS), leading to myocardial hypertrophy and fibrosis. Several …

Myocardial sodium–glucose cotransporter 2 expression and cardiac remodelling in patients with severe aortic stenosis: The BIO‐AS study

L Scisciola, P Paolisso, M Belmonte… - European Journal of …, 2024 - Wiley Online Library
Aim Cardiac remodelling plays a major role in the prognosis of patients with aortic stenosis
(AS) and could impact the benefits of aortic valve replacement. Our study aimed to evaluate …

Biomarkers as prognostic markers for aortic stenosis: a review

A Sarkar, S Chowdhury, A Kumar, B Khan… - The American Journal of …, 2023 - Elsevier
Aortic stenosis (AS) is the most frequent valvular heart disease among the older individuals.
Current guidelines indicate intervention for patients with symptomatic or fast progressive …

Mixed aortic stenosis and regurgitation: a clinical conundrum

R Nedadur, D Belzile, A Farrell, W Tsang - Heart, 2023 - heart.bmj.com
Mixed aortic stenosis (AS) and aortic regurgitation (AR) is the most frequent concomitant
valve disease worldwide and represents a heterogeneous population ranging from mild AS …

Value of NT-proBNP and Galectin-3 as Biomarkers in the Follow-Up of Asymptomatic Elderly Patients with Severe Aortic Stenosis

M Ramos, M Quezada-Feijoó, R Ayala… - Journal of Clinical …, 2023 - mdpi.com
Recognizing symptoms in elderly patients with severe aortic stenosis (AS) can be a
challenge. Serum biomarkers such as Galectin-3 or N-terminal prohormone B-type …

Severe aortic valve stenosis and pulmonary hypertension: a systematic review of non-invasive ways of risk stratification, especially in patients undergoing …

E Boxhammer, AE Berezin, V Paar, N Bacher… - Journal of Personalized …, 2022 - mdpi.com
Patients with severe aortic valve stenosis and concomitant pulmonary hypertension show a
significantly reduced survival prognosis. Right heart catheterization as a preoperative …

Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis

L Kanwischer, X Xu, AB Saifuddin, S Maamari, X Tan… - Clinical …, 2023 - Springer
Background Aortic stenosis (AS) is one of the most common cardiac diseases and major
cause of morbidity and mortality in the elderly. Transcatheter aortic valve implantation (TAVI) …

Novel Biomarkers and Advanced Cardiac Imaging in Aortic Stenosis: Old and New

A Drăgan, AD Mateescu - Biomolecules, 2023 - mdpi.com
Currently, the symptomatic status and left ventricular ejection fraction (LVEF) play a crucial
role in aortic stenosis (AS) assessment. However, the symptoms are often subjective, and …