Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated
indefinitely in the primitive undifferentiated state while remaining pluripotent; they share …

The heart develops from two bilateral heart fields that are formed during early gastrulation. In
recent years, signaling pathways that specify cardiac mesoderm have been extensively …

Abstract The International Stem Cell Initiative characterized 59 human embryonic stem cell
lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques …

The anterior–posterior axis of the mouse embryo is established by two distinct organizing
centres in the anterior visceral endoderm and the distal primitive streak,,,,,,. These …

Following gastrulation and establishment of the three embryonic germ layers, the first
definitive organ to form in the embryo is the heart, whose morphogenesis, growth, and …

Protein kinase CK2 (formerly casein kinase II) is a highly conserved and ubiquitous
serine/threonine kinase that is composed of two catalytic subunits (CK2α and/or CK2α′) …

Introduction 3. The EGF-related growth factors 4. The EGF-CFC family 5. The erbB receptor
family 6. EGF-like growth factors in cell proliferation and oncogenesis 6.1 The EGF-like …

Hematopoietic stem cells (HSCs) are maintained in hypoxic niches in endosteal regions of
bones. Here we demonstrate that Cripto and its receptor GRP78 are important regulators of …

The anterior heart field (AHF) mediates formation of the outflow tract (OFT) and right ventricle
(RV) during looping morphogenesis of the heart. Foxh1 is a forkhead DNA binding …

It is increasingly evident that genes known to perform critical roles during early
embryogenesis, particularly during stem cell renewal, pluripotentiality and survival, are also …