Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …

Stimulation or tolerance of natural killer (NK) cells is achieved through a cross‐talk of signals
derived from cell surface activating and inhibitory receptors. Killer cell immunoglobulin‐like …

The functions of human natural killer (NK) cells are controlled by diverse families of antigen
receptors. Prominent among these are the killer cell immunoglobulin‐like receptors (KIR), a …

Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class-I molecule that was found
to be expressed by placental trophoblast cells 20 years ago. Because trophoblast forms the …

Natural killer (NK) cells are innate immune effector cells that make up~ 10-15% of the
peripheral blood lymphocytes in humans and are primarily involved in immunosurveillance …

Natural killer cells constitute a potent, rapid part of the innate immune response to infection
or transformation, and also generate a link to priming of adaptive immunity. Their function …

Killer‐cell immunoglobulin‐like receptors (KIR s) are components of two fundamental
biological systems essential for human health and survival. First, they contribute to host …

Human leukocyte antigen (HLA)-G is a nonclassical MHC Class I molecule, which was
initially reported as a mediator of immune tolerance when expressed in extravillous …

Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural
killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic …

Purpose Killer-cell immunoglobulin-like receptors (KIRs) that regulate natural-killer cells are
highly polymorphic. Some KIR2DL1 alleles encode receptors that have stronger signaling …