Structure and molecular basis of spermatid elongation in the Drosophila testis

Q Huang, X Chen, H Yu, L Ji, Y Shi… - Open …, 2023 - royalsocietypublishing.org
Spermatid elongation is a crucial event in the late stage of spermatogenesis in the
Drosophila testis, eventually leading to the formation of mature sperm after meiosis. During …

Redox-driven signaling: 2-oxo acid dehydrogenase complexes as sensors and transmitters of metabolic imbalance

VI Bunik - Antioxidants & redox signaling, 2019 - liebertpub.com
Significance: This article develops a holistic view on production of reactive oxygen species
(ROS) by 2-oxo acid dehydrogenase complexes. Recent Advances: Catalytic and structural …

[HTML][HTML] Single-cell RNA-sequencing reveals the transcriptional landscape of ND-42 mediated spermatid elongation via mitochondrial derivative maintenance in …

J Yu, Z Li, Y Fu, F Sun, X Chen, Q Huang, L He, H Yu… - Redox Biology, 2023 - Elsevier
During spermatogenesis, mitochondria extend along the whole length of spermatid tail and
offer a structural platform for microtubule reorganization and synchronized spermatid …

Analysis of Drosophila melanogaster testis transcriptome

V Vedelek, L Bodai, G Grézal, B Kovács, IM Boros… - BMC genomics, 2018 - Springer
Background The formation of matured and individual sperm involves a series of molecular
and spectacular morphological changes of the developing cysts in Drosophila melanogaster …

Identification of cryptic subunits from an apicomplexan ATP synthase

D Huet, E Rajendran, GG van Dooren, S Lourido - Elife, 2018 - elifesciences.org
The mitochondrial ATP synthase is a macromolecular motor that uses the proton gradient to
generate ATP. Proper ATP synthase function requires a stator linking the catalytic and rotary …

Condensed mitochondria assemble into the acrosomal matrix during spermiogenesis

M Ren, Y Xu, CKL Phoon… - Frontiers in Cell and …, 2022 - frontiersin.org
Mammalian spermatogenesis is associated with the transient appearance of condensed
mitochondria, a singularity of germ cells with unknown function. Using proteomic analysis …

Differential expression of nuclear-encoded mitochondrial protein genes of ATP synthase across different tissues of female buffalo

EM Sadeesh, MS Lahamge, A Malik… - Molecular Biotechnology, 2024 - Springer
The physiological well-being of buffaloes, encompassing phenotypic traits, reproductive
health, and productivity, depends on their energy status. Mitochondria, the architects of …

Mutation in Drosophila concentrative nucleoside transporter 1 alters spermatid maturation and mating behavior

HO Maaroufi, L Pauchova, YH Lin, BCH Wu… - Frontiers in Cell and …, 2022 - frontiersin.org
Concentrative nucleoside transporters (Cnts) are unidirectional carriers that mediate the
energy-costly influx of nucleosides driven by the transmembrane sodium gradient. Cnts are …

Adenine nucleotide translocase 2 (Ant2) is required for individualization of spermatogenesis of Drosophila melanogaster

Z He, Y Fang, F Zhang, Y Liu, X Cheng, J Wang… - Insect …, 2024 - Wiley Online Library
Successful completion of spermatogenesis is crucial for the perpetuation of the species. In
Drosophila, spermatid individualization, a process involving changes in mitochondrial …

Cytochrome c1-like is required for mitochondrial morphogenesis and individualization during spermatogenesis in Drosophila melanogaster

MY Chen, X Duan, Q Wang, MJ Ran… - Journal of …, 2023 - journals.biologists.com
The Drosophila testis is an excellent system for studying the process from germ stem cells to
motile sperm, including the proliferation of male germ cells, meiosis of primary …