Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications
D Salvemini, SF Kim, V Mollace - American Journal of …, 2013 - journals.physiology.org
The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities.
Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX …
Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX …
[HTML][HTML] Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes
S Cuzzocrea, D Salvemini - Kidney international, 2007 - Elsevier
The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities.
NO is the mediator generated from the NO synthase (NOS) pathway and COX converts …
NO is the mediator generated from the NO synthase (NOS) pathway and COX converts …
The role of cyclooxygenase in gastric mucosal protection
K Gudis, C Sakamoto - Digestive diseases and sciences, 2005 - Springer
Abstract COX-1 and COX-2 are two cyclooxygenase enzymes responsible for prostanoid
production. COX-2 is expressed in inflammatory cells and fibroblasts of the gastric mucosa …
production. COX-2 is expressed in inflammatory cells and fibroblasts of the gastric mucosa …
Consensus development conference on the use of nonsteroidal anti-inflammatory agents, including cyclooxygenase-2 enzyme inhibitors and aspirin
CM Wilcox, J Allison, K Benzuly, M Borum… - Clinical …, 2006 - cghjournal.org
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly
used medications in the world. Well-recognized gastrointestinal (GI) complications and …
used medications in the world. Well-recognized gastrointestinal (GI) complications and …
Dysphagia and other manifestations of oesophageal involvement in the musculoskeletal diseases
NJ Sheehan - Rheumatology, 2008 - academic.oup.com
Oesophageal dysfunction can occur in a variety of musculoskeletal conditions, most notably
the autoimmune connective tissue diseases. However, correlation between oesophageal …
the autoimmune connective tissue diseases. However, correlation between oesophageal …
COX-2 inhibitors celecoxib and parecoxib: valuable options for postoperative pain management
NM Gajraj - Current topics in medicinal chemistry, 2007 - ingentaconnect.com
COX-2 inhibitors are equally as efficacious as the non-selective NSAIDs for the treatment of
postoperative pain, but have the advantages of a better gastrointestinal side-effect profile as …
postoperative pain, but have the advantages of a better gastrointestinal side-effect profile as …
Isolation of alkaloidal and glycosidal fractions from leaves of Trigonella foenum-graecum L. cv. Desi indigenous to Pakistan for antiprostaglandin evaluation as …
Ethnopharmacological relevance Trigonella foenum graecum (fenugreek) has been in use
for a long time as a traditional medicine and natural food additive. The reported gastro …
for a long time as a traditional medicine and natural food additive. The reported gastro …
Role of cyclooxygenase-2 inhibitors in postoperative pain management
NM Gajraj, GP Joshi - Anesthesiology Clinics of North …, 2005 - anesthesiology.theclinics.com
The acceptance of the concept of multimodal analgesia and the availability of parenteral
preparations of nonsteroidal anti-inflammatory drugs (NSAIDs) have increased the …
preparations of nonsteroidal anti-inflammatory drugs (NSAIDs) have increased the …
Misoprostol elevates intracellular calcium in Neuro-2a cells via protein kinase A
J Tamiji, DA Crawford - Biochemical and biophysical research …, 2010 - Elsevier
Misoprostol, a prostaglandin type E analogue, has been implicated in a number of
neurodevelopmental disorders. However, its mode of action in the nervous system is not …
neurodevelopmental disorders. However, its mode of action in the nervous system is not …
Cardiovascular risks of cyclooxygenase inhibition
ZA Stacy, PP Dobesh, TC Trujillo - … : The Journal of Human …, 2006 - Wiley Online Library
Millions of patients use nonsteroidal antiinflammatory drugs (NSAIDs) for relief of arthritic
pain. Although NSAIDs reduce pain, their use has been linked to gastroduodenal …
pain. Although NSAIDs reduce pain, their use has been linked to gastroduodenal …