Steatotic liver disease: pathophysiology and emerging pharmacotherapies
M Kokkorakis, E Muzurović, Š Volčanšek… - Pharmacological …, 2024 - ASPET
Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype.
Consequently, the metabolic dysfunction-associated steatotic liver disease …
Consequently, the metabolic dysfunction-associated steatotic liver disease …
Sarcopenia, sarcopenic obesity and nonalcoholic fatty liver disease
SA Polyzos, ID Vachliotis, CS Mantzoros - Metabolism, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), sarcopenia and sarcopenic obesity (SO) are
highly prevalent conditions that may coexist, especially in the aging population, without any …
highly prevalent conditions that may coexist, especially in the aging population, without any …
[HTML][HTML] Therapeutic application of natural compounds for skeletal muscle-associated metabolic disorders: A review on diabetes perspective
Skeletal muscle (SM) plays a vital role in energy and glucose metabolism by regulating
insulin sensitivity, glucose uptake, and blood glucose homeostasis. Impaired SM …
insulin sensitivity, glucose uptake, and blood glucose homeostasis. Impaired SM …
Crosstalk between autophagy and insulin resistance: Evidence from different tissues
A Sadeghi, M Niknam… - European Journal of …, 2023 - Springer
Insulin is a critical hormone that promotes energy storage in various tissues, as well as
anabolic functions. Insulin resistance significantly reduces these responses, resulting in …
anabolic functions. Insulin resistance significantly reduces these responses, resulting in …
Sarcopenia: still in relative definition-penia and severe treatment-penia
SA Polyzos, CS Mantzoros - Metabolism, 2023 - Elsevier
Sarcopenia derives from the Greek words “sarx”(ie, flesh) and “penia”(ie, deficiency), and
denotes the decline in the quantity (ie, number of motor units) and quality (atrophy of muscle …
denotes the decline in the quantity (ie, number of motor units) and quality (atrophy of muscle …
GABA prevents age-related sarcopenic obesity in mice with high-fat-diet-induced obesity
H Jin, HJ Oh, BY Lee - Cells, 2023 - mdpi.com
Sarcopenic obesity is characterized by concurrent obesity and muscle wasting (sarcopenia)
and is common in the elderly. Sarcopenic obesity has steadily increased as the aging …
and is common in the elderly. Sarcopenic obesity has steadily increased as the aging …
Celecoxib ameliorates diabetic sarcopenia by inhibiting inflammation, stress response, mitochondrial dysfunction, and subsequent activation of the protein …
C Deng, C Lu, K Wang, M Chang, Y Shen… - Frontiers in …, 2024 - frontiersin.org
Aim: Diabetic sarcopenia leads to disability and seriously affects the quality of life. Currently,
there are no effective therapeutic strategies for diabetic sarcopenia. Our previous studies …
there are no effective therapeutic strategies for diabetic sarcopenia. Our previous studies …
Advances in sarcopenia: mechanisms, therapeutic targets, and intervention strategies
Y Zheng, J Feng, Y Yu, M Ling, X Wang - Archives of Pharmacal Research, 2024 - Springer
Sarcopenia is a multifactorial condition characterized by loss of muscle mass. It poses
significant health risks in older adults worldwide. Both pharmacological and non …
significant health risks in older adults worldwide. Both pharmacological and non …
[HTML][HTML] Sarcopenic obesity and osteoporosis: Research progress and hot spots
S Fan, Y Cai, Y Wei, J Yang, J Gao, Y Yang - Experimental Gerontology, 2024 - Elsevier
Sarcopenic obesity (SO) and osteoporosis (OP) are associated with aging and obesity. The
pathogenesis of SO is complex, including glucolipid and skeletal muscle metabolic …
pathogenesis of SO is complex, including glucolipid and skeletal muscle metabolic …
Control of muscle satellite cell function by specific exercise‐induced cytokines and their applications in muscle maintenance
Q Guo, Q Luo, G Song - Journal of Cachexia, Sarcopenia and …, 2024 - Wiley Online Library
Exercise is recognized to play an observable role in improving human health, especially in
promoting muscle hypertrophy and intervening in muscle mass loss‐related diseases …
promoting muscle hypertrophy and intervening in muscle mass loss‐related diseases …