Rational Design and Lead Optimisation of Potent Antimalarial Quinazolinediones and Their Cytotoxicity against MCF-7
S Charoensutthivarakul, D Lohawittayanan… - Molecules, 2023 - mdpi.com
Quinazolinedione is one of the most outstanding heterocycles in medicinal chemistry thanks
to its wide ranges of biological activities including antimalarial, anticancer, and anti …
to its wide ranges of biological activities including antimalarial, anticancer, and anti …
[HTML][HTML] Solvent-free and eco-friendly green protocol for N-Boc Protection of amines using picric acid as a catalyst
We have developed an environmentally conscious green protocol to protect amine
functional groups in drug discovery and the total synthesis of biologically active natural …
functional groups in drug discovery and the total synthesis of biologically active natural …
Asymmetric Synthesis of Trifluoroethyl-Based, Chiral 3-Benzyloxy-1-and-2-Phenyl-quinazolinones of Biomedicinal Interest by Radical Type Cross-Coupling to Olefins
CT Chen, YC Chang, PX Tseng, CI Lein… - International journal of …, 2022 - mdpi.com
Several 2-substituted (H, Ph, and S-Me) and 1-substituted (H, Ph, and Bn), 3-hydroxy-1, 3-
quinazolin (di) ones were utilized for the first time as radical trapping agents in asymmetric 1 …
quinazolin (di) ones were utilized for the first time as radical trapping agents in asymmetric 1 …
DMAP-Catalyzed Domino Reactions of α-Chloroaldoxime O-Methanesulfonates and 2-Aminobenzoic Acids for the Synthesis of Quinazolinediones
W Kaewman, J Kaeobamrung - Synlett, 2023 - thieme-connect.com
Quinazolinedione derivatives were obtained from 2-aminobenzoic acids and bench-stable α-
chloroaldoxime O-methanesulfonates via DMAP-catalyzed domino reactions under mild …
chloroaldoxime O-methanesulfonates via DMAP-catalyzed domino reactions under mild …